{"id":"W4378516541","doi":"10.3390/pharmaceutics15051401","title":"Prosthetic Joint Infections: Biofilm Formation, Management, and the Potential of Mesoporous Bioactive Glass as a New Treatment Option","year":2023,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Orthopedic Infections and Treatments","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Bioactive glass; Joint arthroplasty; Antibiotics; Medicine; Biomaterial; Biofilm; Bone cement; Joint replacement; Intensive care medicine; Arthroplasty; Surgery; Dentistry; Biomedical engineering; Materials science; Cement; Biology; Microbiology; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002589495,0.0005206749,0.0007459654,0.001780414,0.0002001964,0.0006220138,0.0003444415,0.0008284039,0.001819076],"category_scores_gemma":[0.0002805542,0.0001838547,0.0005231221,0.0008204866,0.0002567679,0.0007343187,0.0003363818,0.000930313,0.0005469209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003318748,"about_ca_system_score_gemma":0.0005792958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008190434,"about_ca_topic_score_gemma":0.001892299,"domain_scores_codex":[0.9998606,0.00001957285,0.00001785517,0.00002129553,0.00006446669,0.00001606724],"domain_scores_gemma":[0.9998887,0.0000526872,0.00002188205,0.000002667541,0.00002595204,0.000008026268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007206682,0.0001667924,0.0003554263,0.04140556,0.0001252494,0.0004499465,0.0001327146,0.0003952876,0.01760707,0.003624187,0.01215346,0.9235122],"study_design_scores_gemma":[0.00002344228,0.0004188276,0.002486996,0.00705058,0.0002679804,0.003963854,0.0001614024,0.0003196672,0.007069395,0.00190053,0.9762998,0.00003752222],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004112409,0.9984145,0.000130611,0.0001855777,0.0000965752,0.000004455169,0.00001175647,0.00000524002,0.0007400989],"genre_scores_gemma":[0.002726062,0.9962062,0.0003041891,0.000148874,0.0000872575,0.000006846049,0.00002129952,0.000001157623,0.0004981743],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001819076,"threshold_uncertainty_score":0.006085396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1002727624060516,"score_gpt":0.3990127447590207,"score_spread":0.298739982352969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}