{"id":"W4378619503","doi":"10.3390/biom13060900","title":"3D Organoids for Regenerative Endodontics","year":2023,"lang":"en","type":"review","venue":"Biomolecules","topic":"Endodontics and Root Canal Treatments","field":"Dentistry","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mesenchymal stem cell; Periodontitis; Pulp (tooth); Regeneration (biology); Regenerative medicine; Tissue engineering; Stem cell; Biology; Cell biology; Dentistry; Medicine; Biomedical engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001345437,0.0005384294,0.001362937,0.0002321361,0.0001605306,0.0001319088,0.0003944793,0.0004126648,0.00004208989],"category_scores_gemma":[0.0001908893,0.0004092476,0.0007877572,0.0004239439,0.00008750624,0.00003048545,0.0001448493,0.0001563314,0.001372419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001621174,"about_ca_system_score_gemma":0.0002265532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000281759,"about_ca_topic_score_gemma":0.0001713122,"domain_scores_codex":[0.9980056,0.0001079701,0.0005864043,0.0005984148,0.0002657779,0.0004357881],"domain_scores_gemma":[0.9985871,0.0002821266,0.0003409277,0.0005390142,0.0001226529,0.0001282163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001136551,0.0001809024,0.000005692777,0.02223249,0.003101768,0.001151638,0.00003573328,3.318198e-7,0.0000288773,0.01214643,0.05943813,0.9016666],"study_design_scores_gemma":[0.0003355225,0.00007075225,8.854794e-7,0.003162578,0.00152919,0.00006012478,0.000008637354,0.000006728893,0.0001260458,0.0001050456,0.9941722,0.0004223525],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000002249667,0.9931185,0.001432067,0.00001340665,0.001506921,0.001093874,0.001818727,0.0001733518,0.0008409523],"genre_scores_gemma":[0.000001386199,0.9623452,0.002843154,0.00001902648,0.0005310749,0.0003664868,0.001307817,0.0002236294,0.03236217],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.934734,"threshold_uncertainty_score":0.9998359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1502006337081562,"score_gpt":0.4152010266275342,"score_spread":0.265000392919378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}