{"id":"W4378627787","doi":"10.2147/jpr.s400682","title":"Efficacy and Safety of SIKD1977 in Combination with Standard Treatment for Postherpetic Neuralgia: Study Protocol for a Double Blind, Placebo-Controlled, Randomized, Multicenter, Phase 2 Clinical Trial","year":2023,"lang":"en","type":"article","venue":"Journal of Pain Research","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Korea Health Industry Development Institute","keywords":"Medicine; Postherpetic neuralgia; Placebo; Randomized controlled trial; Clinical trial; Adverse effect; Visual analogue scale; Quality of life (healthcare); Physical therapy; Neuropathic pain; Surgery; Anesthesia; Internal medicine; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02249024,0.0001497133,0.001280143,0.0006227072,0.0001267641,0.00003662452,0.0000663994,0.00008260483,0.00001782436],"category_scores_gemma":[0.002910225,0.00008284167,0.0002954961,0.0003602275,0.0001410671,0.00006878889,0.00001865996,0.0002685371,8.817602e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002633643,"about_ca_system_score_gemma":0.0004680697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004955679,"about_ca_topic_score_gemma":0.00006803278,"domain_scores_codex":[0.9958148,0.001773299,0.001323625,0.0002080289,0.0005857675,0.0002944898],"domain_scores_gemma":[0.9897148,0.0087174,0.0004039566,0.0001657262,0.0008355676,0.0001625342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9421577,0.0170964,0.001672746,0.0001193798,0.0009424803,0.00007985201,0.0004837039,0.00001868075,0.00001245766,0.00001469715,0.0001163093,0.03728553],"study_design_scores_gemma":[0.8686573,0.1256548,0.0001993613,0.0002660608,0.0002990945,0.000007932727,0.0005497786,0.002369274,0.0000593518,0.00004197844,0.001842964,0.00005207221],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6647039,0.00000938784,0.000453675,0.0005095972,0.00004078809,0.3342454,0.00001002869,0.000006387048,0.00002083283],"genre_scores_gemma":[0.7847567,0.00003618315,0.0006028948,0.000008586293,0.0001425407,0.2141239,0.000008171279,0.00002995181,0.0002910723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1201215,"threshold_uncertainty_score":0.7794714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2281442411979908,"score_gpt":0.5577822184590354,"score_spread":0.3296379772610446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}