{"id":"W4378678568","doi":"10.1007/978-3-031-24345-5_5","title":"Autosomal and X-Linked Degenerative Ataxias: From Genetics to Promising Therapeutics","year":2023,"lang":"en","type":"book-chapter","venue":"Contemporary clinical neuroscience","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Disease; Medicine; Cerebellar ataxia; Ataxia; Neuroscience; Bioinformatics; Biology; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002987276,0.0005731775,0.0005964377,0.0006644425,0.0002662607,0.00164941,0.0006613255,0.001252637,0.01342219],"category_scores_gemma":[0.0003107915,0.0001866376,0.0001919707,0.0006667808,0.0008106959,0.001668821,0.0006948768,0.00191612,0.005205411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006553152,"about_ca_system_score_gemma":0.0006146386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005826234,"about_ca_topic_score_gemma":0.002169833,"domain_scores_codex":[0.9999021,0.00001613217,0.000004739009,0.0000137727,0.0000532792,0.000009943584],"domain_scores_gemma":[0.9998946,0.00006146768,0.000006768499,0.000004538533,0.0000160967,0.00001652759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001003263,0.00009337668,0.0001525792,0.0007654595,0.00001530947,0.0006052266,0.0002627062,0.0005681838,0.005714125,0.1694272,0.295108,0.5271876],"study_design_scores_gemma":[0.00001428488,0.00003646926,0.0002126904,0.0003021421,0.000006657196,0.001276861,0.00005930038,0.0001491276,0.0004646677,0.04438549,0.9530836,0.000008713935],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001312969,0.8180652,0.005484171,0.01243046,0.004084102,0.00001917427,0.0001128735,0.0001651577,0.1583259],"genre_scores_gemma":[0.01300173,0.6375775,0.007578701,0.00841561,0.003869604,0.00006359609,0.0001582451,0.00008198797,0.3292529],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01342219,"threshold_uncertainty_score":0.04490173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1470225424628918,"score_gpt":0.3430775341213307,"score_spread":0.1960549916584389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}