{"id":"W4378715409","doi":"10.1038/s41590-023-01508-y","title":"Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities","year":2023,"lang":"en","type":"article","venue":"Nature Immunology","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; National Institute of Allergy and Infectious Diseases; Medical Research Council; Snow Medical; University of Melbourne; State Government of Victoria; Australian Government; Menzies School of Health Research; American Lebanese Syrian Associated Charities; Division of Intramural Research, National Institute of Allergy and Infectious Diseases; St. Jude Children's Research Hospital; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Coronavirus disease 2019 (COVID-19); Immune system; 2019-20 coronavirus outbreak; Immunology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Pandemic; Betacoronavirus; Coronavirus Infections; Biology; Medicine; Disease; Pathology; Outbreak; Infectious disease (medical specialty)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.000462158,0.0002397956,0.0005248436,0.001056231,0.0002646726,0.0000383212,0.0002421418,0.0007625919,0.00006065267],"category_scores_gemma":[0.01141844,0.0002052193,0.00008109506,0.001440131,0.0002341548,0.0001008973,0.0002087434,0.001417467,0.00005177943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002818899,"about_ca_system_score_gemma":0.0008170397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005866701,"about_ca_topic_score_gemma":0.003926944,"domain_scores_codex":[0.9981233,0.0002241043,0.000382826,0.0004257977,0.0002880724,0.0005558868],"domain_scores_gemma":[0.9966998,0.002581184,0.000093063,0.0003966159,0.0001612754,0.00006802488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02158122,0.0009512412,0.7053119,0.002201562,0.0007083083,0.001648801,0.005473756,0.00000660875,0.2207657,0.002944469,0.03747307,0.0009333992],"study_design_scores_gemma":[0.006702661,0.0007091376,0.755788,0.0002383191,0.00003984204,0.0003948422,0.002919884,0.00009697046,0.01589757,0.0002533435,0.2166505,0.0003089655],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9560659,0.01324779,0.00001638316,0.02863764,0.0001607771,0.001208398,0.0001157568,0.000287457,0.0002598946],"genre_scores_gemma":[0.9898236,0.0008128209,0.0000468634,0.008490242,0.00006598428,0.0003754091,0.0001070863,0.00003707355,0.0002408622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2048681,"threshold_uncertainty_score":0.9969088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04505937013539493,"score_gpt":0.3583732852975096,"score_spread":0.3133139151621147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}