{"id":"W4378745318","doi":"10.3389/ti.2023.10936","title":"Normothermic Ex Vivo Machine Perfusion of Discarded Human Pancreas Allografts: A Feasibility Study","year":2023,"lang":"en","type":"article","venue":"Transplant International","topic":"Organ Transplantation Techniques and Outcomes","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"Government of Canada","keywords":"Medicine; Pancreas; Perfusion; Ex vivo; Transplantation; Pancreas transplantation; Machine perfusion; Edema; Organ donation; Surgery; In vivo; Pathology; Urology; Internal medicine; Kidney transplantation; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002725545,0.000160597,0.0002996478,0.0002384709,0.00005374168,0.00001030217,0.0001852269,0.00006149246,0.001341024],"category_scores_gemma":[0.000009047297,0.0001288296,0.0001659439,0.0001826098,0.00005075159,0.00006185524,0.00001548284,0.0001425428,0.00003190045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004347389,"about_ca_system_score_gemma":0.00002826696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003344751,"about_ca_topic_score_gemma":0.0002055937,"domain_scores_codex":[0.9986204,0.00004602604,0.0004191882,0.0002692604,0.0004829518,0.0001622114],"domain_scores_gemma":[0.9994801,0.00005639413,0.0000813002,0.000224266,0.00008352655,0.00007444715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006267083,0.0008076322,0.9217406,0.0001727194,0.0001816322,0.0001395942,0.001927783,0.000004581215,0.0735969,0.0002960856,0.0001720608,0.0003337119],"study_design_scores_gemma":[0.003318674,0.0005007189,0.9773481,0.0001573662,0.0002485019,0.0000767419,0.0002071364,0.0003609276,0.0172663,0.0001550097,0.0002062156,0.0001543016],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950325,0.00001887196,0.0004557028,0.0005773676,0.0001431733,0.0006454731,0.0005131789,0.0002842214,0.00232948],"genre_scores_gemma":[0.9974658,0.0002156557,0.0001523636,0.00009404172,0.00006120918,0.00001903977,0.0005841975,0.00002494547,0.001382709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0563306,"threshold_uncertainty_score":0.9995719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03124410191907628,"score_gpt":0.341303938165648,"score_spread":0.3100598362465717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}