{"id":"W4378782966","doi":"10.1128/spectrum.01254-23","title":"Choreography of Lyme Disease Spirochete Adhesins To Promote Vascular Escape","year":2023,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Government of Canada","keywords":"Borrelia burgdorferi; Lyme disease; Tick; Biology; Bacterial adhesin; Pathogen; Ixodes; Borrelia; Disease; Host (biology); Virology; Microbiology; Zoology; Immunology; Ecology; Medicine; Virulence; Genetics; Antibody; Pathology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001172249,0.0001442073,0.00009000669,0.0001595064,0.0001226626,0.0002676012,0.00007494514,0.000204977,0.0009647623],"category_scores_gemma":[0.0001030951,0.0000849885,0.0001099887,0.00004816971,0.0001356876,0.0001752018,0.0001510893,0.0003176205,0.0001729859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001842903,"about_ca_system_score_gemma":0.0001185187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005644041,"about_ca_topic_score_gemma":0.0009204496,"domain_scores_codex":[0.999935,0.00001475028,0.000002267112,0.00001166131,0.00001104831,0.00002515916],"domain_scores_gemma":[0.9998865,0.00002858282,0.00001975461,0.0000114992,0.00002374272,0.00002988212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006424106,0.00001163219,0.0005379623,0.00001599817,0.000001547769,0.00007833731,0.00002805997,0.00002453435,0.9982186,0.0002454611,0.00002693279,0.000746605],"study_design_scores_gemma":[0.00001708218,0.0007009492,0.03847082,0.00002237538,0.00001651878,0.0006550734,0.0002139265,0.001866348,0.953918,0.0002338157,0.00387675,0.000008373132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936759,0.001645953,0.002870203,0.00006401907,0.0000146363,0.00001312185,0.00004817003,0.00003306724,0.001634853],"genre_scores_gemma":[0.9950575,0.0005043712,0.001995622,0.00004200007,0.000005807514,0.000009935434,0.00004927911,0.000006277749,0.002329211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009647623,"threshold_uncertainty_score":0.003227472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007404805195793829,"score_gpt":0.2207314215263598,"score_spread":0.2133266163305659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}