{"id":"W4378953050","doi":"10.1128/spectrum.00137-23","title":"Overexpression of Eimeria tenella Rhoptry Kinase 2 Induces Early Production of Schizonts","year":2023,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Coccidia and coccidiosis research","field":"Agricultural and Biological Sciences","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancéropôle Grand Ouest; Université François-Rabelais; Centre National de la Recherche Scientifique; Ministère de l'Éducation et de l'Enseignement supérieur; Conseil Régional de Bretagne; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; Agence Nationale de la Recherche; Sorbonne Université; Infrastructures en Biologie Santé et Agronomie","keywords":"Rhoptry; Biology; Cell biology; Toxoplasma gondii; Protein kinase A; Kinase; MAPK/ERK pathway; Dense granule; Microneme; Molecular biology; Apicomplexa; Immunology; Plasmodium falciparum","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001215815,0.0004022154,0.0001821615,0.000221301,0.0001006713,0.000237077,0.0001446751,0.0002063863,0.001029087],"category_scores_gemma":[0.0001172579,0.0001244441,0.0002199798,0.0001467424,0.0001493212,0.0001422406,0.0001807452,0.0004834256,0.0004292176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003702179,"about_ca_system_score_gemma":0.0001905468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001005779,"about_ca_topic_score_gemma":0.001810456,"domain_scores_codex":[0.9998621,0.00002326761,0.00001496761,0.00002069979,0.00003512165,0.00004376955],"domain_scores_gemma":[0.9998791,0.00002428779,0.00003240422,0.00001661343,0.00001161934,0.00003600419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005613228,0.00001027242,0.00004142824,0.00001242837,0.00000132261,0.00002210027,0.000004774698,0.00002148693,0.9996008,0.00003219817,0.00001710645,0.0001799854],"study_design_scores_gemma":[0.00001513669,0.0002193459,0.003386965,0.000003913998,0.000006637244,0.0001128477,0.00002773151,0.0009824799,0.9935849,0.00003179078,0.001624372,0.000003799603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920912,0.001070312,0.002827826,0.0001036291,0.00006017141,0.00006140688,0.0009234491,0.0002435537,0.002618378],"genre_scores_gemma":[0.9909796,0.0004064112,0.002219961,0.00003772524,0.000006281671,0.00003013084,0.001342078,0.00003129465,0.004946458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001029087,"threshold_uncertainty_score":0.003442585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01878057923368505,"score_gpt":0.2394020596430285,"score_spread":0.2206214804093434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}