{"id":"W4378953050","doi":"10.1128/spectrum.00137-23","title":"Overexpression of Eimeria tenella Rhoptry Kinase 2 Induces Early Production of Schizonts","year":2023,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Coccidia and coccidiosis research","field":"Agricultural and Biological Sciences","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancéropôle Grand Ouest; Université François-Rabelais; Centre National de la Recherche Scientifique; Ministère de l'Éducation et de l'Enseignement supérieur; Conseil Régional de Bretagne; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; Agence Nationale de la Recherche; Sorbonne Université; Infrastructures en Biologie Santé et Agronomie","keywords":"Rhoptry; Biology; Cell biology; Toxoplasma gondii; Protein kinase A; Kinase; MAPK/ERK pathway; Dense granule; Microneme; Molecular biology; Apicomplexa; Immunology; Plasmodium falciparum","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002487385,0.0001157816,0.0002332018,0.0000502145,0.00009436024,0.000008538103,0.0002696564,0.000145295,0.0003146742],"category_scores_gemma":[0.00006206133,0.00004812621,0.00009602904,0.000640816,0.0001547563,0.00005704641,0.0001647824,0.0001340037,0.00008849715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000125861,"about_ca_system_score_gemma":0.00001516035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003800161,"about_ca_topic_score_gemma":0.0001189007,"domain_scores_codex":[0.9989049,0.0001302146,0.0002563468,0.0003145191,0.00008151001,0.0003125061],"domain_scores_gemma":[0.9995829,0.00008963853,0.0001268416,0.0001014305,0.00005405592,0.00004510225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008770013,0.00006502087,0.02167081,0.00001278901,0.0000184807,0.000001460006,0.00005171367,0.000001281751,0.9718942,0.00004677934,0.0008802238,0.005269538],"study_design_scores_gemma":[0.00008067937,0.0002604636,0.2605585,0.00004360394,0.000004296196,0.000005121768,0.00007502767,0.000001133621,0.7378054,0.0003310706,0.0007565968,0.0000780898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980755,0.0001606492,1.107577e-7,0.0009481176,0.0002402305,0.0001800951,0.00003926075,0.00005199948,0.0003040387],"genre_scores_gemma":[0.9991785,0.000122261,0.00001355661,0.00001323593,0.0001444071,0.000008742893,0.00009177277,0.000001311988,0.0004262317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2388877,"threshold_uncertainty_score":0.3445462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01878057923368505,"score_gpt":0.2394020596430285,"score_spread":0.2206214804093434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}