{"id":"W4378983268","doi":"10.1002/jbm4.10758","title":"A Phase I Randomized Trial of Once‐Daily Versus <scp>Twice‐Daily</scp> Recombinant Human Parathyroid Hormone (1‐84) for Hypoparathyroidism","year":2023,"lang":"en","type":"article","venue":"JBMR Plus","topic":"Thyroid and Parathyroid Surgery","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Takeda Pharmaceuticals U.S.A.","keywords":"Hypoparathyroidism; Parathyroid hormone; Recombinant DNA; Medicine; Hormone; Internal medicine; Endocrinology; Calcium; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001999896,0.001521283,0.003133525,0.0004003488,0.0004098518,0.0009533731,0.0008381068,0.001494112,0.004798693],"category_scores_gemma":[0.001757845,0.0006509422,0.001390963,0.0003880062,0.001141097,0.0008133038,0.0003027092,0.002831358,0.0007606583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006140964,"about_ca_system_score_gemma":0.001197314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006918744,"about_ca_topic_score_gemma":0.001148433,"domain_scores_codex":[0.9993052,0.00040446,0.00003623349,0.0001240135,0.00005018978,0.00007990217],"domain_scores_gemma":[0.9987172,0.0004390044,0.0002512139,0.000114756,0.00008584079,0.0003919876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9819388,0.006581943,0.0002218612,0.000289435,0.0004027442,0.00002217892,0.00002515275,0.0002026371,0.003216759,0.00007750525,0.0003791157,0.00664188],"study_design_scores_gemma":[0.8947598,0.1030787,0.0007638257,0.00001292505,0.0002013931,0.00001983921,0.00001091254,0.0004085646,0.0003509282,0.0000865414,0.0002972528,0.000009304965],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874306,0.003054346,0.0008591327,0.0004713938,0.0006737043,0.005178815,0.0007428083,0.0001505728,0.001438715],"genre_scores_gemma":[0.9845631,0.002072226,0.001851531,0.0009401079,0.0006068178,0.006406979,0.0008448063,0.00003429039,0.002680289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004798693,"threshold_uncertainty_score":0.0160532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05786591201678766,"score_gpt":0.3530365711355228,"score_spread":0.2951706591187351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}