{"id":"W4379093552","doi":"10.1007/s11248-023-00351-z","title":"A novel approach to achieving more efficient production of the mature form of human IL-37 in plants","year":2023,"lang":"en","type":"article","venue":"Transgenic Research","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Biology; Signal peptide; Fusion protein; Computational biology; Protease; Gene; Cell biology; Peptide sequence; Genetics; Biochemistry; Recombinant DNA; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003684635,0.0008021998,0.000438733,0.0003669913,0.0003231369,0.0006102241,0.0005835498,0.0006525192,0.0009149807],"category_scores_gemma":[0.000188735,0.0003366077,0.0007086891,0.0002654633,0.0005129119,0.0005101059,0.0005392786,0.00205099,0.0005016853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005883937,"about_ca_system_score_gemma":0.0006117533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007655542,"about_ca_topic_score_gemma":0.0009946583,"domain_scores_codex":[0.9997728,0.00003370266,0.00002056751,0.00005789419,0.00007811227,0.00003693121],"domain_scores_gemma":[0.9998228,0.00004037684,0.00004581137,0.00003553057,0.00002097226,0.00003455499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001715058,0.00001082784,0.00001279332,0.00002265509,0.000002581662,0.00003926334,0.000009514171,0.00003518271,0.9985799,0.0003274188,0.00003681242,0.0009058171],"study_design_scores_gemma":[0.00001602821,0.0001009292,0.0001615884,0.000004822806,0.00001954371,0.0003463287,0.00001173956,0.000439341,0.9928261,0.0002101634,0.005853396,0.0000100659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4266303,0.006286202,0.5546266,0.001920436,0.0007447467,0.0006648189,0.001189591,0.00181312,0.00612421],"genre_scores_gemma":[0.7128083,0.005396747,0.2664091,0.0005859951,0.0001409805,0.0003972757,0.001458155,0.0002903318,0.01251307],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0009149807,"threshold_uncertainty_score":0.004269063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0767832885240488,"score_gpt":0.3661838118148388,"score_spread":0.28940052329079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}