{"id":"W4379094715","doi":"10.1002/ejhf.2924","title":"Effect of Phosphodiesterase-5 Inhibition on Systemic Right Ventricular Size and Function. A Multicentre, Double-Blind, Randomized, Placebo-Controlled Trial: SERVE","year":2023,"lang":"en","type":"article","venue":"European Journal of Heart Failure","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Universitätsspital Zürich; Inselspital, Universitätsspital Bern","keywords":"Medicine; Double blind; Placebo; Randomized controlled trial; Heart failure; Phosphodiesterase; Internal medicine; Cardiology; Enzyme; Biochemistry; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002768043,0.001526719,0.003295851,0.0004856685,0.0004988277,0.001241574,0.0008554836,0.003082962,0.006427813],"category_scores_gemma":[0.001779197,0.0006312049,0.002030847,0.0004036431,0.001096533,0.0007878217,0.0003985554,0.001786817,0.0009088832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004788173,"about_ca_system_score_gemma":0.001065339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004371114,"about_ca_topic_score_gemma":0.000903939,"domain_scores_codex":[0.9989078,0.000575131,0.0001262845,0.0001962738,0.00008553159,0.0001088917],"domain_scores_gemma":[0.9989606,0.0002606251,0.0003813284,0.00009189489,0.00008564426,0.0002199813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9828953,0.003425928,0.0002986975,0.001257993,0.0007227579,0.00002271202,0.00002217929,0.00008977733,0.003002729,0.00005331487,0.0002977373,0.007910901],"study_design_scores_gemma":[0.9663834,0.03144813,0.0008734438,0.00003808165,0.0003797359,0.00001828698,0.000005655049,0.000152004,0.0003973658,0.00003307629,0.0002649672,0.000005936316],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9670643,0.01928832,0.001046831,0.0008659011,0.001244565,0.005835148,0.001511964,0.0001985773,0.002944305],"genre_scores_gemma":[0.9807147,0.00472537,0.002443826,0.001464179,0.001160921,0.005902187,0.001089805,0.00002902234,0.002469973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006427813,"threshold_uncertainty_score":0.02150321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0140350847232532,"score_gpt":0.2727114675351939,"score_spread":0.2586763828119407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}