{"id":"W4379095028","doi":"10.34067/kid.0000000000000171","title":"Insights into the Regulation of GFR by the Keap1-Nrf2 Pathway","year":2023,"lang":"en","type":"article","venue":"Kidney360","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Chemistry; Endocrinology; Internal medicine; TRPC; Contractility; Activator (genetics); Renal function; Kidney; KEAP1; Receptor; Cell biology; Transient receptor potential channel; Biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001413485,0.00008823474,0.0001369372,0.00004821727,0.0001271326,0.00001360243,0.0001069737,0.00004585773,0.00008175415],"category_scores_gemma":[0.0002549712,0.00004071149,0.00009914359,0.0004314433,0.0001287848,0.00004491871,0.00004787728,0.00009673807,0.0001385233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000157728,"about_ca_system_score_gemma":0.00008139502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001136298,"about_ca_topic_score_gemma":0.00001017586,"domain_scores_codex":[0.9991954,0.00005713796,0.0001861279,0.000130014,0.0003081803,0.0001231403],"domain_scores_gemma":[0.9992914,0.00009770511,0.00006980947,0.0003698907,0.00007438866,0.00009679775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002462327,0.0001691729,0.005267587,0.0004065546,0.0001799024,0.00002045396,0.01096367,0.00003733546,0.2273946,0.01292646,0.6947563,0.04763178],"study_design_scores_gemma":[0.0009852641,0.0002469619,0.3582837,0.0002679405,0.0001445936,0.000007780144,0.001677442,0.001491386,0.03400501,0.01255819,0.5901635,0.0001682097],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9717512,0.003156948,0.00002864015,0.01593467,0.0002412448,0.000377892,0.00002252165,0.00009136524,0.008395523],"genre_scores_gemma":[0.993356,0.0003232021,0.00001193246,0.0009963198,0.0001407324,0.00002484974,0.00009593755,0.00001321722,0.005037739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3530161,"threshold_uncertainty_score":0.1780483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0115614439284671,"score_gpt":0.2503855113331301,"score_spread":0.238824067404663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}