{"id":"W4379095028","doi":"10.34067/kid.0000000000000171","title":"Insights into the Regulation of GFR by the Keap1-Nrf2 Pathway","year":2023,"lang":"en","type":"article","venue":"Kidney360","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Chemistry; Endocrinology; Internal medicine; TRPC; Contractility; Activator (genetics); Renal function; Kidney; KEAP1; Receptor; Cell biology; Transient receptor potential channel; Biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004538889,0.0005441477,0.0004587729,0.0004157925,0.0002793539,0.0005733452,0.000357975,0.0004241653,0.00251961],"category_scores_gemma":[0.0001614299,0.0001378916,0.0005183783,0.0002101105,0.0003334901,0.001018642,0.0003986885,0.0009266359,0.0004011333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004002885,"about_ca_system_score_gemma":0.0004176131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004657759,"about_ca_topic_score_gemma":0.0006376989,"domain_scores_codex":[0.9998311,0.0000271243,0.00001299022,0.00004495537,0.00004478408,0.00003897363],"domain_scores_gemma":[0.9998429,0.00001344568,0.00004429503,0.00001494396,0.00005501671,0.00002929331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008549917,0.0001670072,0.004267999,0.002079242,0.0001777264,0.0009172469,0.0002080936,0.001070361,0.9182286,0.01133519,0.002105173,0.05858831],"study_design_scores_gemma":[0.0002743903,0.002164443,0.1166697,0.0007635452,0.000671234,0.007355508,0.001664309,0.01279951,0.6573088,0.03298737,0.1671579,0.0001833488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6980501,0.1896125,0.06891727,0.01087261,0.0007650941,0.0001451916,0.002771651,0.0007046553,0.02816094],"genre_scores_gemma":[0.947848,0.03475581,0.00923908,0.0008774594,0.000179128,0.00006143952,0.0005324939,0.00003367115,0.006472952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00251961,"threshold_uncertainty_score":0.008428931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0115614439284671,"score_gpt":0.2503855113331301,"score_spread":0.238824067404663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}