{"id":"W4379230326","doi":"10.3390/cancers15113036","title":"Creation of EGD-Derived Gastric Cancer Organoids to Predict Treatment Responses","year":2023,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Center for Advancing Translational Sciences","keywords":"Medicine; Clinical trial; Cancer; Biopsy; Internal medicine; Drug; Oncology; Chemotherapy; Surrogate endpoint; Perioperative; Surgery; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008383332,0.0004801526,0.0005491051,0.000574981,0.0001570601,0.0007636411,0.0003037888,0.0004706036,0.0006573792],"category_scores_gemma":[0.001193353,0.0002638922,0.0003912566,0.0002154228,0.0002387235,0.0003660408,0.0007569668,0.0006665695,0.0004527887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002418913,"about_ca_system_score_gemma":0.0002113865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002954344,"about_ca_topic_score_gemma":0.0004960787,"domain_scores_codex":[0.9996282,0.00007768127,0.00003588766,0.0001161283,0.0001139758,0.0000281704],"domain_scores_gemma":[0.9994173,0.0001699469,0.0001199598,0.0001171805,0.00009695056,0.00007865339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005410076,0.00008133161,0.02527809,0.000134722,0.00006158542,0.0003076938,0.0001690295,0.00370762,0.9403177,0.0001684091,0.0003849689,0.02884799],"study_design_scores_gemma":[0.00005256494,0.001056932,0.04696109,0.00005011492,0.000169297,0.001519134,0.0002841812,0.03589427,0.9048743,0.0003350007,0.008735008,0.00006829736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8762996,0.002232767,0.1152386,0.0002703237,0.0001369014,0.0004579992,0.002415083,0.0009777533,0.001970921],"genre_scores_gemma":[0.9210261,0.0008535691,0.07450092,0.0001766634,0.0000215127,0.0002387119,0.00233222,0.00006894548,0.0007814167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008383332,"threshold_uncertainty_score":0.004433632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03580049687635792,"score_gpt":0.3283748033434431,"score_spread":0.2925743064670852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}