{"id":"W4379261098","doi":"10.1016/j.nbd.2023.106179","title":"Reduction of aggressive behaviour following hypothalamic deep brain stimulation: Involvement of 5-HT1A and testosterone","year":2023,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Deep brain stimulation; Testosterone (patch); Amygdala; Stimulation; 5-HT1A receptor; Psychology; Endocrinology; Orbitofrontal cortex; Internal medicine; Antagonist; 5-HT receptor; Medicine; Serotonin; Receptor; Neuroscience; Prefrontal cortex; Cognition","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000811318,0.0002870563,0.0002781895,0.000103069,0.00009830458,0.0001339839,0.00009551978,0.0001688772,0.001091633],"category_scores_gemma":[0.0001142,0.00009288127,0.0001954513,0.00007114494,0.0002147929,0.00007686661,0.0001338598,0.0004955768,0.0001107427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001496899,"about_ca_system_score_gemma":0.0001418325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008256107,"about_ca_topic_score_gemma":0.002263567,"domain_scores_codex":[0.9999453,0.00001503309,0.000003698536,0.000006911099,0.00001409551,0.00001494909],"domain_scores_gemma":[0.9999409,0.000007240093,0.00002035156,0.000005634784,0.00000415052,0.00002168434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.006175199,0.0008023293,0.01222082,0.0002529862,0.000185386,0.001177758,0.0001624165,0.0001812574,0.9383801,0.0001523203,0.0003298975,0.0399796],"study_design_scores_gemma":[0.0006269875,0.0212736,0.7809521,0.00004974525,0.0003811234,0.005505633,0.0004402925,0.001904518,0.1844452,0.0004611839,0.003923929,0.00003570286],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969209,0.001609104,0.0003617651,0.00009527637,0.00001872219,0.0000132373,0.00007178387,0.00001946536,0.0008896557],"genre_scores_gemma":[0.9978077,0.001010386,0.0002627747,0.00007369056,0.00001578788,0.00001858245,0.0000988598,0.000002913259,0.0007093158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001091633,"threshold_uncertainty_score":0.003651857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02384208665747229,"score_gpt":0.282283451462876,"score_spread":0.2584413648054037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}