{"id":"W4379280261","doi":"10.1056/nejmoa2304594","title":"Overall Survival with Osimertinib in Resected <i>EGFR</i> -Mutated NSCLC","year":2023,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":612,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"AstraZeneca","keywords":"Medicine; Osimertinib; Internal medicine; Hazard ratio; Placebo; Clinical endpoint; Lung cancer; Regimen; Population; Oncology; Surgery; Confidence interval; Cancer; Clinical trial; Epidermal growth factor receptor; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005088511,0.0001396326,0.0004730496,0.0003899748,0.00003367982,0.000006767368,0.00007211368,0.00004717168,0.0001972333],"category_scores_gemma":[0.0002541283,0.00007780948,0.00004290621,0.0007093137,0.00005984757,0.00008397349,0.00001049143,0.0003157839,0.00001191708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001071179,"about_ca_system_score_gemma":0.0004363706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004735355,"about_ca_topic_score_gemma":0.0002409722,"domain_scores_codex":[0.9985622,0.00007046477,0.0004609493,0.000128743,0.0005377331,0.0002399009],"domain_scores_gemma":[0.9989545,0.0002175673,0.0001931843,0.0001376224,0.0002120326,0.0002850438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02698984,0.0008614506,0.5117085,0.0002832494,0.002613948,0.02310222,0.01967359,0.001464169,0.0380911,0.0005331751,0.150032,0.2246468],"study_design_scores_gemma":[0.3535835,0.009009226,0.5580348,0.003032559,0.001074505,0.002362594,0.001247202,0.0002490365,0.0008428463,0.0007058778,0.06959198,0.0002659465],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9707304,0.0006294597,0.0001073345,0.02176456,0.000511476,0.0002229703,0.000003353847,0.000040742,0.005989746],"genre_scores_gemma":[0.9952894,0.0003334073,0.0001952199,0.0005604554,0.001459588,0.000002675306,0.00004014317,0.00002455078,0.002094583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3265936,"threshold_uncertainty_score":0.3172978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02339926590478572,"score_gpt":0.3316075296963627,"score_spread":0.308208263791577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}