{"id":"W4379280327","doi":"10.1101/2023.05.31.23290594","title":"Protein Vaccine Demonstrates Less Reactogenicity than mRNA – A Real World Study","year":2023,"lang":"en","type":"preprint","venue":"medRxiv","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Novavax","keywords":"Reactogenicity; Booster (rocketry); Medicine; Coronavirus disease 2019 (COVID-19); Observational study; Booster dose; Virology; Internal medicine; Immunology; Immunogenicity; Infectious disease (medical specialty); Disease; Aerospace engineering; Immunization; Engineering; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002570341,0.0002177038,0.0002896415,0.0003809068,0.0002387082,0.0009462508,0.0002075401,0.0004090885,0.002225508],"category_scores_gemma":[0.004492682,0.0001685555,0.0003157441,0.000598523,0.0005420501,0.0004877541,0.0003289234,0.0004467744,0.0004099805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003131737,"about_ca_system_score_gemma":0.0003599085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004194802,"about_ca_topic_score_gemma":0.003033816,"domain_scores_codex":[0.9978563,0.001239282,0.000132532,0.0003728686,0.0002290009,0.0001699675],"domain_scores_gemma":[0.9946897,0.001261344,0.002780821,0.000555039,0.0004511973,0.0002619261],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001185835,0.0001392099,0.9955597,0.00003287064,0.0001754431,0.00006060279,0.000106089,0.00006679104,0.0006550877,0.00005460124,0.0001734721,0.0017902],"study_design_scores_gemma":[0.00003693917,0.001028981,0.9971697,0.00001349617,0.00008065796,0.0002022366,0.0002830091,0.000216938,0.0002540448,0.00004096209,0.000666733,0.000006335007],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983509,0.0003600914,0.0001550354,0.00005716438,0.000008417315,0.000009161246,0.0003189693,0.000002117691,0.0007380915],"genre_scores_gemma":[0.9994195,0.00008444044,0.00005103804,0.00005259598,0.00001088631,0.00000347698,0.0002887537,0.000001374966,0.00008802072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004194802,"threshold_uncertainty_score":0.01359344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1132730397592343,"score_gpt":0.3830379493341445,"score_spread":0.2697649095749103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}