{"id":"W4379281765","doi":"10.1200/jco.2023.41.16_suppl.7550","title":"Glofitamab monotherapy in pts with relapsed/refractory (R/R) large B-cell lymphoma (LBCL): Extended follow-up and landmark analyses from a pivotal phase II study.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"","keywords":"Medicine; Refractory (planetary science); Post-hoc analysis; Regimen; Phases of clinical research; Nuclear medicine; Clinical endpoint; Internal medicine; Toxicity; Urology; Surgery; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001990667,0.0007986028,0.0010933,0.0003077005,0.0002469252,0.0008375344,0.0005960112,0.0005257248,0.001810442],"category_scores_gemma":[0.0009541934,0.0003078704,0.001051657,0.0004918529,0.0003425272,0.0006242132,0.0004747904,0.001376262,0.0004692119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008923184,"about_ca_system_score_gemma":0.0007832976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008865082,"about_ca_topic_score_gemma":0.002803653,"domain_scores_codex":[0.9995149,0.0002438307,0.00003118786,0.00007217989,0.00005818587,0.00007972809],"domain_scores_gemma":[0.9992948,0.0001250717,0.0002263352,0.00006934312,0.00004453006,0.0002398784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7450705,0.01496528,0.06385528,0.001540774,0.004649965,0.0006276022,0.0004924298,0.003716617,0.03916357,0.0002282807,0.008517098,0.1171727],"study_design_scores_gemma":[0.3057055,0.4137486,0.2530546,0.0001769152,0.003916354,0.001348244,0.0002170297,0.002431821,0.00656073,0.0003023167,0.01243851,0.00009936391],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898986,0.00413741,0.000546915,0.0002551618,0.00003629456,0.001089228,0.002567085,0.0000596227,0.001409529],"genre_scores_gemma":[0.9880376,0.001573152,0.00102046,0.0004629377,0.00007492752,0.0008393686,0.006830868,0.00002224207,0.001138452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001990667,"threshold_uncertainty_score":0.01052773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1495203005649964,"score_gpt":0.5083827260818493,"score_spread":0.3588624255168529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}