{"id":"W4379282239","doi":"10.1200/jco.2023.41.16_suppl.tps5116","title":"PSMAddition: A phase 3 trial to compare treatment with <sup>177</sup>Lu-PSMA-617 plus standard of care (SoC) and SoC alone in patients with metastatic hormone-sensitive prostate cancer.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Prostate cancer; Androgen deprivation therapy; Clinical endpoint; Oncology; Internal medicine; Enzalutamide; Urology; Cancer; Randomized controlled trial; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001344329,0.00181132,0.002025703,0.0004511616,0.0003785897,0.001031651,0.001215483,0.001370671,0.01120432],"category_scores_gemma":[0.001082291,0.0005119389,0.00174307,0.0004358611,0.001265259,0.001024585,0.0004772229,0.002814328,0.001401436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009813588,"about_ca_system_score_gemma":0.001992332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009641424,"about_ca_topic_score_gemma":0.003099558,"domain_scores_codex":[0.999667,0.0001683374,0.00001543269,0.0000594887,0.00002488652,0.00006479015],"domain_scores_gemma":[0.9992037,0.0001485145,0.00016187,0.00006344145,0.00003335098,0.0003890647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9561562,0.01320447,0.001358455,0.0004664654,0.0006141998,0.00005307026,0.00006328804,0.0007165007,0.004058961,0.0002192436,0.001683484,0.02140562],"study_design_scores_gemma":[0.8820031,0.1136859,0.002385024,0.00001996758,0.0001742613,0.00005539176,0.00002492021,0.0003184837,0.0004453458,0.0001610469,0.0007141142,0.00001252817],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855649,0.001795616,0.0005408523,0.0006516052,0.000355205,0.004689243,0.00241521,0.0002506954,0.003736728],"genre_scores_gemma":[0.98256,0.001240019,0.001440238,0.001326452,0.0002702108,0.004793923,0.003850817,0.00003740782,0.004480944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01120432,"threshold_uncertainty_score":0.0374822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1116587552999057,"score_gpt":0.4791463726981037,"score_spread":0.367487617398198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}