{"id":"W4379282849","doi":"10.1200/jco.2023.41.16_suppl.8521","title":"Clinical outcomes with neoadjuvant nivolumab (N) + chemotherapy (C) vs C by definitive surgery in patients (pts) with resectable NSCLC: 3-y results from the phase 3 CheckMate 816 trial.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Internal medicine; Surgery; Clinical endpoint; Oncology; Phases of clinical research; Neoadjuvant therapy; Chemotherapy; Randomized controlled trial; Gastroenterology; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001209057,0.0004396541,0.0008511636,0.0001241862,0.0001952397,0.0005608885,0.0003274291,0.0005792505,0.001607614],"category_scores_gemma":[0.0007535804,0.0001671281,0.001042241,0.0001788265,0.0004253085,0.0003992951,0.0002366508,0.001137481,0.000279005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006742371,"about_ca_system_score_gemma":0.0006155907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006548557,"about_ca_topic_score_gemma":0.002441473,"domain_scores_codex":[0.9997459,0.0001451487,0.00001663439,0.0000412523,0.00001888201,0.00003213234],"domain_scores_gemma":[0.9994522,0.0001176485,0.000179449,0.00004025961,0.00002221465,0.0001883438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9094973,0.006499923,0.01549981,0.0006718909,0.001362172,0.00006286681,0.00009470224,0.001369598,0.007961328,0.0001090142,0.002410799,0.05446066],"study_design_scores_gemma":[0.4854895,0.4237705,0.07890332,0.0001651375,0.002538775,0.0003145476,0.0001074073,0.002347467,0.00296715,0.0003455073,0.003001865,0.00004884537],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966879,0.001996876,0.00009315889,0.000138165,0.00005105163,0.0001873708,0.0003001018,0.00001654646,0.0005286901],"genre_scores_gemma":[0.9971299,0.000729452,0.0002744709,0.0003823654,0.00008514631,0.0002610807,0.0006197885,0.000005445558,0.0005123875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001607614,"threshold_uncertainty_score":0.006394148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1136324293690017,"score_gpt":0.4904432246227921,"score_spread":0.3768107952537905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}