{"id":"W4379282877","doi":"10.1200/jco.2023.41.16_suppl.5002","title":"Prognostic impact of PSA nadir (n) ≥0.1 ng/mL within 6 months (m) after completion of radiotherapy (RT) for localized prostate cancer (PCa): An individual patient-data (IPD) analysis of randomized trials from the ICECAP collaborative.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre; McMaster University; London Health Sciences Centre","funders":"","keywords":"Medicine; Androgen deprivation therapy; Prostate cancer; Proportional hazards model; Internal medicine; Randomization; Oncology; Radiation therapy; Stage (stratigraphy); Surrogate endpoint; Randomized controlled trial; Clinical endpoint; Hazard ratio; Urology; Survival analysis; Cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.02567212,0.000901314,0.002478737,0.0008266608,0.0003556907,0.001936093,0.001434985,0.001210881,0.003896806],"category_scores_gemma":[0.03059642,0.0003931522,0.006520908,0.00120111,0.0005435621,0.001322992,0.001141008,0.001848255,0.0003330891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001065052,"about_ca_system_score_gemma":0.00176926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001519388,"about_ca_topic_score_gemma":0.002990334,"domain_scores_codex":[0.9857884,0.01111942,0.0008971044,0.001073633,0.0007070523,0.0004142745],"domain_scores_gemma":[0.9607042,0.0257609,0.008404516,0.002711641,0.0008654677,0.001553277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.5587282,0.00135128,0.2983708,0.005472557,0.06487099,0.0001434832,0.0001970124,0.004031447,0.0007314743,0.0005083482,0.008687859,0.05690647],"study_design_scores_gemma":[0.1527966,0.04434252,0.6527693,0.001594786,0.1140992,0.0009260065,0.0003747396,0.01290487,0.001758641,0.00266003,0.01554607,0.0002271649],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9304603,0.03885369,0.002932607,0.001260486,0.0003074901,0.001872985,0.02050079,0.00009302986,0.003718525],"genre_scores_gemma":[0.9867623,0.001582898,0.001623642,0.0005184751,0.0002028775,0.00108449,0.007517416,0.00004066661,0.0006671913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9975213,"threshold_uncertainty_score":0.1357688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2661617005470177,"score_gpt":0.553959838353273,"score_spread":0.2877981378062553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}