{"id":"W4379283603","doi":"10.1200/jco.2023.41.16_suppl.tps2680","title":"Abatacept for immune checkpoint inhibitor associated myocarditis (ATRIUM): Phase 3, investigator-initiated, randomized, placebo-controlled study to evaluate the efficacy and safety of abatacept compared to placebo in hospitalized patients with immune checkpoint inhibitor associated myocarditis.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Abatacept; Placebo; Internal medicine; Mace; Myocarditis; Adverse effect; Population; Myocardial infarction; Rituximab; Pathology; Percutaneous coronary intervention","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002283377,0.00173695,0.003455843,0.0004690114,0.0006127467,0.001000476,0.001159189,0.002478906,0.008200683],"category_scores_gemma":[0.001558035,0.0007678494,0.00194839,0.0003681075,0.001200793,0.001120388,0.0003767977,0.003763071,0.001223692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006895008,"about_ca_system_score_gemma":0.001640952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005658643,"about_ca_topic_score_gemma":0.001625266,"domain_scores_codex":[0.9992828,0.000348907,0.00004532879,0.0001241672,0.00006029011,0.0001385299],"domain_scores_gemma":[0.9988179,0.000258915,0.0002931162,0.0000831561,0.00009438074,0.0004524492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9632552,0.01649209,0.0006368491,0.0006558074,0.0005689606,0.00005393121,0.00004155776,0.0001862667,0.004975275,0.0000785874,0.0008140935,0.01224134],"study_design_scores_gemma":[0.9181001,0.0800695,0.0009433373,0.00002115466,0.0001357493,0.00002770253,0.000009266124,0.0001523697,0.0002531976,0.00005079202,0.0002303999,0.000006512498],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722679,0.004963005,0.001229963,0.0007842777,0.0007048944,0.01546191,0.002223545,0.0002764835,0.002087981],"genre_scores_gemma":[0.967584,0.002699285,0.003844648,0.001955158,0.0007894346,0.01869092,0.001745062,0.00003898231,0.002652472],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008200683,"threshold_uncertainty_score":0.02743399,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04999415559325594,"score_gpt":0.392043112508057,"score_spread":0.3420489569148011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}