{"id":"W4379284138","doi":"10.1056/nejmoa2303269","title":"Preoperative Treatment of Locally Advanced Rectal Cancer","year":2023,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":448,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba","funders":"National Cancer Institute; National Institutes of Health; Schweizerische Arbeitsgemeinschaft für Klinische Krebsforschung; NRG Oncology; ECOG-ACRIN Cancer Research Group; American College of Radiology Imaging Network; Alliance for Clinical Trials in Oncology Foundation","keywords":"FOLFOX; Medicine; Hazard ratio; Oxaliplatin; Colorectal cancer; Chemoradiotherapy; Clinical endpoint; Surgery; Internal medicine; Oncology; Confidence interval; Radiation therapy; Randomized controlled trial; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002201493,0.0001705901,0.0007680673,0.0002125432,0.00002579498,0.000002313632,0.00006361507,0.00005127997,0.000597841],"category_scores_gemma":[0.000214735,0.00009444272,0.0001267677,0.000468848,0.0001016558,0.00006219833,0.0000121167,0.0001267336,0.000007938935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002611698,"about_ca_system_score_gemma":0.0004302699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002174671,"about_ca_topic_score_gemma":0.0000963729,"domain_scores_codex":[0.9985694,0.00006171471,0.0005291968,0.0001396052,0.0005028591,0.0001972113],"domain_scores_gemma":[0.9987172,0.0002620566,0.00027029,0.0001319326,0.0002923516,0.0003261048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.01141108,0.0003211173,0.05261957,0.00006209202,0.000843656,0.001581236,0.004330855,0.0003137927,0.01118668,0.0000312245,0.003154494,0.9141442],"study_design_scores_gemma":[0.3930575,0.08853564,0.3176491,0.003868632,0.001924149,0.002423345,0.001181321,0.0003471768,0.03833622,0.0005806263,0.1517212,0.0003750864],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846459,0.004681157,0.00004194762,0.006748549,0.0007605517,0.0003064769,0.000007369908,0.00002316931,0.002784877],"genre_scores_gemma":[0.9885633,0.006137519,0.0002612801,0.0001119056,0.001926578,0.00001053299,0.000008078628,0.00001885031,0.002961982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9137691,"threshold_uncertainty_score":0.6545939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03744182590264006,"score_gpt":0.351940593823846,"score_spread":0.3144987679212059,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}