{"id":"W4379330790","doi":"10.1200/jco.2023.41.16_suppl.tps7592","title":"Phase 3 trial of subcutaneous epcoritamab + R-CHOP versus R-CHOP in patients (pts) with newly diagnosed diffuse large B-cell lymphoma (DLBCL): EPCORE DLBCL-2.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Medicine; Rituximab; Diffuse large B-cell lymphoma; Internal medicine; Vincristine; Cytokine release syndrome; CHOP; Oncology; Prednisone; Phases of clinical research; International Prognostic Index; Cyclophosphamide; Lymphoma; Gastroenterology; Discontinuation; CD20; Clinical trial; Chemotherapy; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001607421,0.002006191,0.001851894,0.0003099461,0.0003098037,0.001010657,0.001027798,0.001252513,0.005974947],"category_scores_gemma":[0.001115328,0.0005908591,0.001323716,0.0003424774,0.0009734849,0.0008780265,0.0004309057,0.004409473,0.001507976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009288237,"about_ca_system_score_gemma":0.001212411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001174973,"about_ca_topic_score_gemma":0.002859487,"domain_scores_codex":[0.9996697,0.0001698672,0.00001047465,0.00005622803,0.00002724154,0.00006647191],"domain_scores_gemma":[0.9993538,0.0001287662,0.0001158751,0.00006318613,0.00003242147,0.0003058681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9221901,0.02543664,0.001324798,0.0004711923,0.0007028619,0.0001329066,0.0001160212,0.001255752,0.009434543,0.0002045694,0.00321453,0.03551606],"study_design_scores_gemma":[0.8422967,0.1515731,0.003005428,0.00002298356,0.0002222472,0.0001287276,0.00002998699,0.0009772982,0.0005641639,0.0002050805,0.0009600119,0.00001424027],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862211,0.00204772,0.000742063,0.0009569603,0.0004599447,0.004029847,0.001884894,0.0002779416,0.003379729],"genre_scores_gemma":[0.9824554,0.001446061,0.001879928,0.001880695,0.0003514397,0.004268301,0.003535628,0.00005188523,0.004130575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005974947,"threshold_uncertainty_score":0.01998818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1036216593571909,"score_gpt":0.4599618155398131,"score_spread":0.3563401561826222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}