{"id":"W4379330790","doi":"10.1200/jco.2023.41.16_suppl.tps7592","title":"Phase 3 trial of subcutaneous epcoritamab + R-CHOP versus R-CHOP in patients (pts) with newly diagnosed diffuse large B-cell lymphoma (DLBCL): EPCORE DLBCL-2.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Medicine; Rituximab; Diffuse large B-cell lymphoma; Internal medicine; Vincristine; Cytokine release syndrome; CHOP; Oncology; Prednisone; Phases of clinical research; International Prognostic Index; Cyclophosphamide; Lymphoma; Gastroenterology; Discontinuation; CD20; Clinical trial; Chemotherapy; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004714005,0.0003420435,0.002800316,0.0006957842,0.00005791131,0.00001942046,0.0005052816,0.0007559257,0.0004920367],"category_scores_gemma":[0.007415629,0.000250595,0.0008353065,0.00102831,0.0003655881,0.0001584301,0.0001584564,0.001530443,0.00009391789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005805387,"about_ca_system_score_gemma":0.002793093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005986014,"about_ca_topic_score_gemma":0.0001506966,"domain_scores_codex":[0.9923208,0.001058075,0.003783742,0.0004670499,0.001527333,0.0008430157],"domain_scores_gemma":[0.9859727,0.009593224,0.002105987,0.0005991649,0.0008899164,0.0008389985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.680355,0.1214018,0.01573705,0.00007128192,0.0004327027,0.01140104,0.0002889616,0.000005941582,0.0003164162,0.00001661249,0.00341678,0.1665565],"study_design_scores_gemma":[0.777863,0.1692945,0.01578735,0.0001386444,0.0002944992,0.0001229005,0.0003009631,0.0001702756,0.00008718429,0.00003947816,0.03570944,0.0001917045],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919299,0.0001164419,0.00001414634,0.001094361,0.003088953,0.001121755,0.00003697151,0.00003066046,0.002566768],"genre_scores_gemma":[0.9948409,0.001332126,0.0003172802,0.0003995407,0.001556089,0.00002089182,0.00002775883,0.00008077352,0.001424669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1663648,"threshold_uncertainty_score":0.9999946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1036216593571909,"score_gpt":0.4599618155398131,"score_spread":0.3563401561826222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}