{"id":"W4379336689","doi":"10.1200/jco.2023.41.16_suppl.tps5612","title":"ARTISTRY-7: A phase 3, multicenter study of nemvaleukin alfa in combination with pembrolizumab versus chemotherapy in patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer (GOG-3063; ENGOT-OV68).","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; London Health Sciences Centre; Hamilton Health Sciences","funders":"","keywords":"Medicine; Pembrolizumab; Tolerability; Internal medicine; Ovarian cancer; Oncology; Chemotherapy; Fallopian tube; Phases of clinical research; Cancer; Fallopian tube cancer; Carboplatin; Serous carcinoma; Response Evaluation Criteria in Solid Tumors; Endometrial cancer; Immunotherapy; Gynecology; Adverse effect; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001894231,0.001393702,0.001575598,0.0004616259,0.0003949798,0.001134666,0.001189827,0.001692191,0.004026721],"category_scores_gemma":[0.000822834,0.0005374682,0.001989065,0.0003880321,0.001082289,0.0009357299,0.0004405416,0.003710544,0.0009827923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001042902,"about_ca_system_score_gemma":0.001665111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001013797,"about_ca_topic_score_gemma":0.003063661,"domain_scores_codex":[0.9995932,0.0001983637,0.0000162198,0.00006135234,0.00004214764,0.00008870061],"domain_scores_gemma":[0.9993193,0.00009663903,0.0001350385,0.00005143887,0.00005181028,0.0003456532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7593752,0.08278697,0.006873073,0.001885423,0.002269627,0.000256193,0.0004245716,0.003444186,0.03923219,0.0006155242,0.007942097,0.09489496],"study_design_scores_gemma":[0.5422657,0.4421245,0.008043733,0.00007417188,0.0005294791,0.0002885307,0.0001096616,0.001059907,0.002176891,0.0002497,0.003041523,0.00003609871],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874007,0.004157566,0.0004621143,0.0007102886,0.0002247198,0.002635014,0.001606098,0.0001142851,0.002689188],"genre_scores_gemma":[0.9844072,0.002854907,0.001608845,0.001633501,0.0002586818,0.002694978,0.003266478,0.00004179267,0.003233659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004026721,"threshold_uncertainty_score":0.01347071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.065304763447694,"score_gpt":0.4247665469622113,"score_spread":0.3594617835145174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}