{"id":"W4379339971","doi":"10.1200/jco.2023.41.16_suppl.7515","title":"Response-adapted therapy (tx) with nivolumab plus brentuximab vedotin (nivo + BV) without autologous hematopoietic cell transplantation (auto-HCT) in children, adolescents, and young adults (CAYA) with low-risk relapsed/refractory (R/R) classic Hodgkin lymphoma (cHL): CheckMate 744.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Internal medicine; Oncology; Cohort; Salvage therapy; Anthracycline; Chemotherapy; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004303813,0.0002588195,0.0004044317,0.000161627,0.0001768195,0.0003001507,0.0003802327,0.00027959,0.001228404],"category_scores_gemma":[0.0003689716,0.0001290792,0.000400406,0.0001695305,0.0001792533,0.0002358696,0.0002822251,0.0007619718,0.0002000476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006255601,"about_ca_system_score_gemma":0.0006254185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001363948,"about_ca_topic_score_gemma":0.005151305,"domain_scores_codex":[0.9998641,0.00004866501,0.00001021721,0.00003292168,0.00001360311,0.00003042905],"domain_scores_gemma":[0.9997867,0.00003514357,0.00004579687,0.0000154676,0.000007211112,0.0001097362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2931438,0.03505395,0.1709066,0.0008431241,0.001466901,0.001206273,0.0007090337,0.006875786,0.04599054,0.000515785,0.007324131,0.4359641],"study_design_scores_gemma":[0.07040998,0.5998507,0.3021851,0.0001950062,0.001558999,0.00211161,0.0002895206,0.005612726,0.00822956,0.0003158443,0.009198357,0.00004255278],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983607,0.0007280676,0.000102927,0.0000468056,0.00001311972,0.0001187344,0.0001858569,0.00001405627,0.0004297537],"genre_scores_gemma":[0.9981214,0.000404147,0.000345878,0.0001477668,0.00001929345,0.00014542,0.0005148802,0.00000331892,0.0002977751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001363948,"threshold_uncertainty_score":0.004538834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02116003616876674,"score_gpt":0.3200773694488376,"score_spread":0.2989173332800709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}