{"id":"W4379341221","doi":"10.1200/jco.2023.41.16_suppl.8523","title":"Response to neoadjuvant immune checkpoint inhibitor (ICI)-based therapy in oncogene-driven resectable non-small cell lung cancer (NSCLC).","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Internal medicine; Nivolumab; Oncology; KRAS; Lung cancer; Gemcitabine; Hazard ratio; Ipilimumab; Exact test; Cancer; Confidence interval; Immunotherapy; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006959407,0.0001509781,0.0003858139,0.0001642085,0.000087929,0.0003161706,0.0001366118,0.0001977665,0.000973044],"category_scores_gemma":[0.0008047651,0.00006343907,0.0004704009,0.0001971514,0.0001396529,0.000197233,0.0001678127,0.0003423878,0.0002557647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004629925,"about_ca_system_score_gemma":0.0003355825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003475182,"about_ca_topic_score_gemma":0.0008320323,"domain_scores_codex":[0.999708,0.0001036468,0.00003905403,0.00007033246,0.0000416204,0.00003732174],"domain_scores_gemma":[0.9995951,0.0001082358,0.0001328283,0.00003067057,0.0000251981,0.0001079914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1763548,0.003073858,0.6396685,0.0009150903,0.001201194,0.000571225,0.0001682366,0.002049839,0.02990813,0.0002016684,0.003167826,0.1427195],"study_design_scores_gemma":[0.003218896,0.05459986,0.9257162,0.00009334233,0.0007941743,0.001500982,0.0001047579,0.002006023,0.005300058,0.0001875821,0.006459597,0.0000185595],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963517,0.001721625,0.0001435084,0.00005786735,0.0000209203,0.00007563307,0.0007577606,0.000008040299,0.0008628544],"genre_scores_gemma":[0.9975889,0.0003318639,0.0001820929,0.00009544737,0.00002122005,0.00007528996,0.001442087,0.000003212517,0.0002599348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000973044,"threshold_uncertainty_score":0.003680527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07769800303543296,"score_gpt":0.4769410763487024,"score_spread":0.3992430733132695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}