{"id":"W4379345488","doi":"10.1200/jco.2023.41.16_suppl.8044","title":"Identification of cytokines associated with response and cytokine release syndrome: Analysis of MagnetisMM-3 cohort A.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Calgary","funders":"Pfizer","keywords":"Medicine; Cytokine; Cohort; Internal medicine; Cytokine release syndrome; Immunology; Gastroenterology; Pharmacology; Immune system; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001059362,0.0003926355,0.0004924961,0.0004565165,0.0004351709,0.0005189597,0.0003416333,0.0004403312,0.001818141],"category_scores_gemma":[0.000871244,0.000161499,0.0007025482,0.0003971253,0.0002018207,0.0003162876,0.0004850948,0.0006815656,0.0004369298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000343384,"about_ca_system_score_gemma":0.000506313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001296943,"about_ca_topic_score_gemma":0.001731648,"domain_scores_codex":[0.9996151,0.00008622645,0.00003130426,0.0001218883,0.00007261465,0.00007286855],"domain_scores_gemma":[0.9991832,0.0001209528,0.0002637538,0.0001170405,0.00009204493,0.0002229671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01940492,0.00077633,0.9554699,0.00005746801,0.0004250732,0.0003195453,0.0001428895,0.0003265986,0.01331836,0.0000801217,0.001874105,0.007804589],"study_design_scores_gemma":[0.0007566105,0.003542013,0.9905004,0.000009877085,0.0001806702,0.0008430636,0.0001115852,0.0007778348,0.001081583,0.00006408893,0.002115044,0.0000173575],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965881,0.0001701896,0.0001479354,0.00003473032,0.000006828483,0.0000765949,0.002635584,0.000009908445,0.0003302095],"genre_scores_gemma":[0.9896927,0.00007136964,0.0003798864,0.0001061165,0.00002827073,0.0002178908,0.008867338,0.00001260917,0.0006237881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001818141,"threshold_uncertainty_score":0.006082296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07945615037243428,"score_gpt":0.4494910918103694,"score_spread":0.3700349414379351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}