{"id":"W4379345526","doi":"10.1200/jco.2023.41.16_suppl.e21159","title":"Retreatment with EGFR inhibitor in non-small cell lung cancer patients previously exposed to EGFR-TKI: A systematic review and meta-analysis.","year":2023,"lang":"en","type":"review","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Gefitinib; Internal medicine; Erlotinib; Oncology; Lung cancer; Meta-analysis; Cochrane Library; Epidermal growth factor receptor; Clinical trial; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008423713,0.001902746,0.01614159,0.005665165,0.0004780384,0.002163609,0.001665834,0.001824947,0.002729279],"category_scores_gemma":[0.01773474,0.00108125,0.03079298,0.007760047,0.0004905924,0.00157386,0.001097868,0.001291501,0.0002722729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002087406,"about_ca_system_score_gemma":0.002810189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007443781,"about_ca_topic_score_gemma":0.0177885,"domain_scores_codex":[0.9943715,0.002261979,0.001922347,0.0005925467,0.000629893,0.0002218246],"domain_scores_gemma":[0.9901741,0.006549732,0.002041723,0.0002593916,0.0008057665,0.000169448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001673695,0.00003061524,0.004728386,0.4885504,0.4919495,0.0001655229,0.00008516465,0.0004556186,0.0002548736,0.0001083288,0.0006750452,0.01132294],"study_design_scores_gemma":[0.000509422,0.0001911637,0.005181292,0.03425677,0.9572905,0.0001191211,0.00005171951,0.0001993376,0.0001149893,0.0001401867,0.001921772,0.00002375301],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00500703,0.9934681,0.0002949303,0.000145626,0.00009609463,0.0002154333,0.0005616095,0.00001375072,0.0001974411],"genre_scores_gemma":[0.1747499,0.8204725,0.001454975,0.0007459359,0.0001705471,0.0009289265,0.00110007,0.00002215625,0.0003550571],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01614159,"threshold_uncertainty_score":0.04454941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1752775036945248,"score_gpt":0.5179745255713109,"score_spread":0.3426970218767861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}