{"id":"W4379365035","doi":"10.1080/2162402x.2023.2214478","title":"Trial watch: immunotherapeutic strategies on the horizon for hepatocellular carcinoma","year":2023,"lang":"en","type":"review","venue":"OncoImmunology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovation Cluster (Canada)","funders":"National Medical Research Council; Medical Research Council; Eisai","keywords":"Medicine; Oncology; Durvalumab; Internal medicine; Hepatocellular carcinoma; Liver transplantation; Bevacizumab; Tremelimumab; Brentuximab vedotin; Nivolumab; Regimen; Atezolizumab; Immunotherapy; Intensive care medicine; Cancer; Transplantation; Ipilimumab; Lymphoma; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000705225,0.0008973671,0.003021662,0.0002888249,0.0003097143,0.00009531427,0.0005440176,0.001079441,0.00019107],"category_scores_gemma":[0.0001184228,0.0005294002,0.001988288,0.000524212,0.0002592174,0.00005015916,0.000103213,0.0009155986,0.00110628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003643738,"about_ca_system_score_gemma":0.001279869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009340196,"about_ca_topic_score_gemma":0.000005490221,"domain_scores_codex":[0.9964918,0.0005510917,0.00103844,0.0008019156,0.0003024222,0.0008142634],"domain_scores_gemma":[0.9962443,0.001705163,0.0004772,0.001381968,0.0001098091,0.00008152041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0088443,0.0006020935,0.0001283922,0.00932451,0.004741119,0.0004510256,0.0002431538,2.647914e-8,0.00002274577,0.008797365,0.001959371,0.9648859],"study_design_scores_gemma":[0.012454,0.007982694,0.000006706337,0.003015399,0.004284289,0.0001025292,0.0001621762,0.00002368908,0.00002912788,0.0003973857,0.9710814,0.0004605964],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004640729,0.9815785,0.00001827601,0.0009639954,0.001376443,0.009813729,0.00009128667,0.0002713476,0.001245707],"genre_scores_gemma":[0.004621311,0.9828148,0.00004080837,0.0001110522,0.0007806382,0.00599555,0.0008983468,0.0002978159,0.004439615],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9691221,"threshold_uncertainty_score":0.9997157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2962444592995445,"score_gpt":0.3671983680449715,"score_spread":0.07095390874542695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}