{"id":"W4379365035","doi":"10.1080/2162402x.2023.2214478","title":"Trial watch: immunotherapeutic strategies on the horizon for hepatocellular carcinoma","year":2023,"lang":"en","type":"review","venue":"OncoImmunology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovation Cluster (Canada)","funders":"National Medical Research Council; Medical Research Council; Eisai","keywords":"Medicine; Oncology; Durvalumab; Internal medicine; Hepatocellular carcinoma; Liver transplantation; Bevacizumab; Tremelimumab; Brentuximab vedotin; Nivolumab; Regimen; Atezolizumab; Immunotherapy; Intensive care medicine; Cancer; Transplantation; Ipilimumab; Lymphoma; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007354249,0.0004556405,0.001016422,0.001113016,0.0001676965,0.0007872566,0.0006684851,0.0008015327,0.005534787],"category_scores_gemma":[0.0009734543,0.0001186439,0.0006494063,0.001095518,0.0001789964,0.0008454105,0.0005300971,0.001729443,0.001923767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004324233,"about_ca_system_score_gemma":0.0008607309,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000452193,"about_ca_topic_score_gemma":0.001431187,"domain_scores_codex":[0.9998116,0.00005574982,0.00002838878,0.00002190448,0.00006127049,0.00002109237],"domain_scores_gemma":[0.9996201,0.0001997771,0.00006174688,0.0000086359,0.00007646691,0.00003327266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001787948,0.00005461405,0.00008762477,0.01921258,0.0001386349,0.00006501879,0.00002935485,0.0001705328,0.0008045902,0.002365881,0.04239861,0.9344937],"study_design_scores_gemma":[0.0001854498,0.0002339654,0.0006775172,0.01143854,0.0003410241,0.000419629,0.00003358585,0.0001078115,0.0003308387,0.001887534,0.9843305,0.00001361481],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001809128,0.9966658,0.0001190848,0.0006798072,0.0004784216,0.00002474866,0.00007542595,0.00001441373,0.001761444],"genre_scores_gemma":[0.001027104,0.9962781,0.0002165833,0.0009438171,0.0003112883,0.00003177927,0.0001447998,0.000004580357,0.001041963],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005534787,"threshold_uncertainty_score":0.01851577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2962444592995445,"score_gpt":0.3671983680449715,"score_spread":0.07095390874542695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}