{"id":"W4379375986","doi":"10.1056/nejmoa2303379","title":"Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma","year":2023,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":733,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Janssen Research and Development","keywords":"Lenalidomide; Multiple myeloma; Refractory (planetary science); Standard of care; Medicine; Internal medicine; Oncology; Biology; Astrobiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001305708,0.0003563,0.0008290396,0.0003778806,0.0002103529,0.0003787894,0.0004936092,0.0007477608,0.002126109],"category_scores_gemma":[0.001393094,0.0001828742,0.0007486448,0.0002886298,0.0005372484,0.000342143,0.0002831478,0.001102585,0.0001306986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006849585,"about_ca_system_score_gemma":0.000721735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006508504,"about_ca_topic_score_gemma":0.001459527,"domain_scores_codex":[0.9994484,0.0003238793,0.00004531417,0.00007038785,0.00004920129,0.00006283945],"domain_scores_gemma":[0.9991154,0.0003453688,0.0002704865,0.0000353365,0.00002614493,0.000207216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8505535,0.012363,0.009540437,0.0006362296,0.0009392549,0.00008218364,0.00009483993,0.001152951,0.004563518,0.0002196267,0.0006948882,0.1191596],"study_design_scores_gemma":[0.6207293,0.3419081,0.02904822,0.0001743889,0.001189142,0.0001747451,0.0000574841,0.002038257,0.002295118,0.0003716643,0.001992305,0.00002137048],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942788,0.004428365,0.000138291,0.0002877189,0.0000735387,0.0002624751,0.00006282802,0.00001799619,0.0004500189],"genre_scores_gemma":[0.9974672,0.001280733,0.0003954056,0.0002850451,0.00009685038,0.0002305185,0.00008590736,0.000002048221,0.0001562447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002126109,"threshold_uncertainty_score":0.007112503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0463347515928686,"score_gpt":0.3503627163535822,"score_spread":0.3040279647607136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}