{"id":"W4379376267","doi":"10.1080/03007995.2023.2219155","title":"Safety and efficacy of aripiprazole 2-month ready-to-use 960 mg: secondary analysis of outcomes in adult patients with bipolar I disorder in a randomized, open-label, parallel-arm, pivotal study","year":2023,"lang":"en","type":"article","venue":"Current Medical Research and Opinion","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brain and Cognition Discovery Foundation; University of Toronto","funders":"National Eye Institute; H. Lundbeck A/S; Otsuka Pharmaceutical","keywords":"Medicine; Aripiprazole; Tolerability; Clinical Global Impression; Adverse effect; Young Mania Rating Scale; Bipolar disorder; Bipolar I disorder; Randomized controlled trial; Clinical endpoint; Visual analogue scale; Internal medicine; Mania; Schizophrenia (object-oriented programming); Mood; Psychiatry; Anesthesia; Placebo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003706649,0.001484463,0.002259388,0.000464267,0.0004104078,0.001010109,0.0007106064,0.001066459,0.003732804],"category_scores_gemma":[0.002820155,0.0005354193,0.003081247,0.0005343808,0.0005457604,0.0007985207,0.0003973169,0.001970915,0.0006705371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006110945,"about_ca_system_score_gemma":0.0009675832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006791331,"about_ca_topic_score_gemma":0.001554937,"domain_scores_codex":[0.998401,0.0007778883,0.0001730411,0.0003190379,0.0001941623,0.0001349491],"domain_scores_gemma":[0.9962458,0.0006056324,0.00183784,0.0002513985,0.0004107799,0.0006484595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9309109,0.01083012,0.02329792,0.0008701936,0.004171597,0.0001383315,0.0001153083,0.0004607143,0.00884895,0.00006477766,0.00131917,0.01897188],"study_design_scores_gemma":[0.6273121,0.2184574,0.1434348,0.00007654123,0.004382581,0.0002971046,0.0000737377,0.001321827,0.002828489,0.0001630852,0.001588794,0.00006364357],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934193,0.001533458,0.0002974759,0.000136296,0.00006826375,0.001299701,0.002139989,0.00003375615,0.001071748],"genre_scores_gemma":[0.9932889,0.0006400241,0.000628064,0.0003056523,0.0002079614,0.001347565,0.002802259,0.00001476284,0.0007648505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003732804,"threshold_uncertainty_score":0.01960289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05695061033023321,"score_gpt":0.4097856326431164,"score_spread":0.3528350223128832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}