{"id":"W4379378240","doi":"10.1016/j.semcdb.2023.05.010","title":"Thrombospondins in the tumor microenvironment","year":2023,"lang":"en","type":"review","venue":"Seminars in Cell and Developmental Biology","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Biology; Tumor microenvironment; Angiogenesis; Immune system; Thrombospondins; Extracellular matrix; Chemokine; Tumor progression; Thrombospondin 1; Cancer research; Immunology; Thrombospondin; Lymphatic system; Cytokine; Cell biology; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007617162,0.001109983,0.001334297,0.00167012,0.0002499614,0.001049987,0.0008842744,0.001376314,0.002348706],"category_scores_gemma":[0.0006624663,0.0002976876,0.0003195212,0.002308811,0.0006109428,0.001286225,0.0008479346,0.002330418,0.001984928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006981458,"about_ca_system_score_gemma":0.001048893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007390513,"about_ca_topic_score_gemma":0.001398366,"domain_scores_codex":[0.9998616,0.0000227816,0.00001580468,0.00002305612,0.0000600312,0.00001661493],"domain_scores_gemma":[0.9997254,0.000122752,0.0000398294,0.000009176281,0.00005650835,0.00004632203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001764763,0.00008034173,0.0001852069,0.008044064,0.00008103258,0.0003200212,0.00003549195,0.0005689421,0.00238587,0.004942659,0.0648061,0.9183738],"study_design_scores_gemma":[0.000062835,0.0001111654,0.0008862321,0.002129866,0.000136254,0.00140672,0.00004146036,0.0001974477,0.0007837752,0.003839453,0.9903839,0.00002098894],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000655819,0.9987011,0.0001239434,0.0002938502,0.0003634224,0.000002128709,0.000009233704,0.000004792447,0.0004360185],"genre_scores_gemma":[0.0005769114,0.9976677,0.000161501,0.0002265069,0.0006825587,0.00000650837,0.00002224849,0.000001267432,0.0006546933],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002348706,"threshold_uncertainty_score":0.007857144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02805872947924149,"score_gpt":0.2985797007652912,"score_spread":0.2705209712860497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}