{"id":"W4379378677","doi":"10.1261/rna.079679.123","title":"Fluorescent labeling of RNA and DNA on the Hoogsteen edge using sulfinate chemistry","year":2023,"lang":"en","type":"article","venue":"RNA","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; University of California, San Diego; National Institutes of Health; Manitoba Medical Service Foundation","keywords":"Nucleic acid; Oligonucleotide; Ribozyme; Azide; Nucleobase; RNA; Linker; DNA; RNA splicing; Biochemistry; Combinatorial chemistry; Nucleoside; Biology; Chemistry; Organic chemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000283086,0.0003227195,0.000189761,0.0002254114,0.0001806587,0.0002999902,0.0003597186,0.0004883087,0.001363494],"category_scores_gemma":[0.0002642157,0.0001698115,0.0001905156,0.0001572086,0.0003675887,0.0004006531,0.0002842988,0.0004772914,0.0004388594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002814141,"about_ca_system_score_gemma":0.000272795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008049936,"about_ca_topic_score_gemma":0.002054291,"domain_scores_codex":[0.9998189,0.00002799693,0.000008133567,0.00004437328,0.00006706572,0.00003353668],"domain_scores_gemma":[0.9998908,0.00003721375,0.00002341297,0.00001305643,0.00001340745,0.00002223394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004070639,0.00001128058,0.00007317353,0.00003040577,0.000003133885,0.00005120794,0.00002439975,0.0002760934,0.9946696,0.001082645,0.00004974635,0.003687666],"study_design_scores_gemma":[0.000004948322,0.0001161945,0.0001819178,0.000002087238,0.000002271474,0.00005485169,0.000006873533,0.0007291194,0.996021,0.0001007856,0.002774687,0.000005283018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9106746,0.00216397,0.0766193,0.0002604468,0.0000804497,0.00006613448,0.000161667,0.0003645262,0.009608976],"genre_scores_gemma":[0.9416941,0.001309949,0.04650458,0.0001213383,0.00002542068,0.00005117016,0.0002280731,0.00006467015,0.0100008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001363494,"threshold_uncertainty_score":0.004561305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03889709670162669,"score_gpt":0.2717840278083006,"score_spread":0.2328869311066739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}