{"id":"W4379381023","doi":"10.20944/preprints202306.0293.v1","title":"Biologically Relevant Murine Models of Chronic<em> Pseudomonas aeruginosa </em>Respiratory Infection","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University; Queen's University Belfast","keywords":"Pseudomonas aeruginosa; Chronic infection; Cystic fibrosis; Microbiology; Lung infection; Antibiotics; Animal model; Biology; Respiratory infection; Pathogen; Antimicrobial; Medicine; Immunology; Lung; Respiratory system; Immune system; Bacteria; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008554115,0.001419917,0.0006111099,0.001526109,0.0006171,0.0008363317,0.0007129102,0.001633706,0.003948369],"category_scores_gemma":[0.0003278061,0.0003122143,0.0008168218,0.0004796544,0.001081996,0.0006907146,0.0006796045,0.002878742,0.001619706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006619769,"about_ca_system_score_gemma":0.0006800545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006221119,"about_ca_topic_score_gemma":0.001000041,"domain_scores_codex":[0.9992183,0.0001437025,0.0001067253,0.0001616146,0.0002054845,0.0001641299],"domain_scores_gemma":[0.9992569,0.00009643202,0.0002168279,0.0001180943,0.00006628757,0.0002455591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007442187,0.0008400506,0.0005689804,0.0002169957,0.00001757195,0.0002987393,0.0001088484,0.0003146431,0.9916608,0.001317779,0.0007168034,0.003194701],"study_design_scores_gemma":[0.0003884612,0.006887906,0.008002911,0.0001621549,0.0001140417,0.002495155,0.0001977386,0.002189712,0.95079,0.001120116,0.02757745,0.00007444296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9154488,0.005131153,0.05373371,0.001561775,0.0008416775,0.001405279,0.01027654,0.001481203,0.01011985],"genre_scores_gemma":[0.8850203,0.006348691,0.05837672,0.001185358,0.0002400756,0.003963396,0.01227762,0.0004225272,0.03216527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003948369,"threshold_uncertainty_score":0.01320857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1236870212710131,"score_gpt":0.3653992358257465,"score_spread":0.2417122145547334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}