{"id":"W4379390159","doi":"10.21203/rs.3.rs-2944450/v1","title":"Association of extensive RNA disruption with natural killer cell-mediated death of K562 chronic myelogenous leukemia cells","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences North; Laurentian University","funders":"Mitacs; Eberhard Karls Universität Tübingen","keywords":"K562 cells; Programmed cell death; Cancer research; RNA; Biology; Leukemia; Cell; Immunology; Apoptosis; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000090366,0.0002187804,0.0001802668,0.0001234142,0.0001132894,0.000202286,0.00007215567,0.0001791984,0.001549406],"category_scores_gemma":[0.00008764079,0.00007304153,0.0001360368,0.0001260563,0.0001345658,0.0001031912,0.0001997537,0.0002004778,0.0006607531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001638792,"about_ca_system_score_gemma":0.00006640689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003395055,"about_ca_topic_score_gemma":0.0002985015,"domain_scores_codex":[0.9998603,0.00002512928,0.00001300047,0.00002781403,0.00003999015,0.00003375962],"domain_scores_gemma":[0.9999459,0.00001038946,0.00001431955,0.00001249656,0.000008169148,0.000008761393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001426503,0.00001797598,0.0007902897,0.00002465836,0.00000455839,0.00009686573,0.00001831133,0.00003187364,0.9980135,0.00004249731,0.00003782764,0.0007790952],"study_design_scores_gemma":[0.00002014127,0.0003919154,0.03572929,0.000004056891,0.000009570665,0.0008773052,0.00005382434,0.000514956,0.9597782,0.00004954201,0.00256739,0.000003862222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943227,0.001096,0.001730175,0.00005174194,0.00001963993,0.00002395782,0.0004163553,0.00003682728,0.002302602],"genre_scores_gemma":[0.9960613,0.0002839818,0.0008534151,0.00003982339,0.000006231475,0.00002591988,0.0005801811,0.000006589777,0.002142668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001549406,"threshold_uncertainty_score":0.00518322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02847756616602669,"score_gpt":0.3120888751808624,"score_spread":0.2836113090148357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}