{"id":"W4379510879","doi":"10.1136/annrheumdis-2023-eular.2565","title":"POS0394 THE CAUSAL RELATIONSHIPS BETWEEN MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR AND OSTEOPOROSIS: EVIDENCE FROM HUMAN STUDIES","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Bone health and osteoporosis research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mendelian randomization; Medicine; Osteoporosis; Linkage disequilibrium; Bone mineral; Internal medicine; Femoral neck; Single-nucleotide polymorphism; Endocrinology; Genetics; Biology; Genotype; Genetic variants","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004542615,0.0006014683,0.0008015129,0.0008203111,0.0004376463,0.001103169,0.0007414427,0.002166642,0.01903022],"category_scores_gemma":[0.01554356,0.0003596271,0.001189333,0.002121096,0.001482113,0.0005828144,0.0004931531,0.0009891678,0.001433921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002386666,"about_ca_system_score_gemma":0.0006317752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002191736,"about_ca_topic_score_gemma":0.002220152,"domain_scores_codex":[0.9975371,0.001634477,0.0002105349,0.0002727727,0.0002470941,0.00009798282],"domain_scores_gemma":[0.9783401,0.01597104,0.003227983,0.00137037,0.0007026421,0.0003878327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.07126276,0.0009566655,0.7013448,0.007529893,0.03287816,0.004002523,0.0005419398,0.001286909,0.007064903,0.005394652,0.009840535,0.1578964],"study_design_scores_gemma":[0.009329954,0.009227859,0.8771414,0.001981575,0.02669523,0.004956784,0.0009430597,0.0007185016,0.002458208,0.01250281,0.05393666,0.000108042],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7119678,0.215387,0.002281842,0.01427649,0.001342509,0.0001689918,0.01432392,0.00009091783,0.04016048],"genre_scores_gemma":[0.9652956,0.02729283,0.0005267769,0.0021492,0.0007429496,0.00003850655,0.002193504,0.00001403778,0.001746599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01903022,"threshold_uncertainty_score":0.06366241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2818330403949761,"score_gpt":0.4319931703412864,"score_spread":0.1501601299463103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}