{"id":"W4379511960","doi":"10.1136/annrheumdis-2023-eular.660","title":"OP0219 INCIDENCE OF MAJOR ADVERSE CARDIOVASCULAR EVENTS IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH JAK-INHIBITORS COMPARED TO BDMARDS: DATA FROM AN INTERNATIONAL COLLABORATION OF REGISTRIES (THE “JAK-POT” STUDY)","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Sanofi Genzyme; Samsung; Alexion Pharmaceuticals; Gilead Sciences; Celltrion; Sanofi; Amgen; Pfizer; Eli Lilly and Company","keywords":"Medicine; Mace; Rheumatoid arthritis; Internal medicine; Incidence (geometry); Cohort; Population; Abatacept; Myocardial infarction; Rituximab; Percutaneous coronary intervention","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001713119,0.0006501919,0.001615223,0.00116807,0.0002394975,0.001319603,0.0006116626,0.0008310549,0.001806095],"category_scores_gemma":[0.003021688,0.0005917603,0.002966196,0.002823328,0.0002819948,0.0008758027,0.0007095686,0.001212651,0.0002840926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002516811,"about_ca_system_score_gemma":0.0004159366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002049291,"about_ca_topic_score_gemma":0.00283842,"domain_scores_codex":[0.9982738,0.0005596036,0.0002663927,0.0004638186,0.0002361586,0.0002001911],"domain_scores_gemma":[0.996852,0.0006982568,0.001743848,0.0002823074,0.000146552,0.0002770953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02561884,0.0001782653,0.9566491,0.000431037,0.008156384,0.0002540977,0.00004979475,0.0002993946,0.001032632,0.0001471581,0.001546,0.005637391],"study_design_scores_gemma":[0.002128609,0.00118059,0.9920878,0.00003455002,0.00293779,0.0003313007,0.00007804389,0.0003061985,0.0001787323,0.00009527556,0.000616275,0.0000248471],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862047,0.00451949,0.0002116624,0.00009891943,0.00008054358,0.00003009909,0.007744988,0.00002080966,0.001088711],"genre_scores_gemma":[0.9904839,0.001692338,0.0001839712,0.0001380955,0.0001450527,0.00004915901,0.006919381,0.00001623459,0.0003719108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002049291,"threshold_uncertainty_score":0.009059906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03013038831871055,"score_gpt":0.3087198097071381,"score_spread":0.2785894213884276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}