{"id":"W4379513592","doi":"10.1136/annrheumdis-2023-eular.615","title":"OP0072 LOW-DOSE COLCHICINE IS ASSOCIATED WITH LOWER INCIDENCE OF KNEE AND HIP REPLACEMENTS: A POST-HOC ANALYSIS FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Heart Research Institute; Radboud Universitair Medisch Centrum; Amsterdam University Medical Centers; McMaster University; Amgen","keywords":"Medicine; Hazard ratio; Placebo; Gout; Osteoarthritis; Randomization; Internal medicine; Interquartile range; Surgery; Post-hoc analysis; Randomized controlled trial; Colchicine; Confidence interval","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002137951,0.002041118,0.006335478,0.0004615172,0.0004416658,0.001623351,0.001016043,0.001744474,0.008410345],"category_scores_gemma":[0.003242099,0.0007805181,0.005219935,0.0005794452,0.001444128,0.001058022,0.0004926355,0.002682511,0.0008074744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006407013,"about_ca_system_score_gemma":0.0009264184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001319524,"about_ca_topic_score_gemma":0.00215978,"domain_scores_codex":[0.9986086,0.0007995971,0.0001217912,0.0002061753,0.0001040701,0.000159825],"domain_scores_gemma":[0.9975325,0.001277734,0.0005005602,0.0001786817,0.0001594975,0.0003510798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9910542,0.000519235,0.0003233062,0.0008549594,0.003602281,0.0000222625,0.00001096333,0.00006422913,0.0008347669,0.00001798011,0.0001741226,0.00252169],"study_design_scores_gemma":[0.9393888,0.04472823,0.005435471,0.00007454016,0.009122937,0.00003745013,0.00003381924,0.0003221665,0.000455862,0.00006867629,0.0002999394,0.00003207777],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9780733,0.01505196,0.0007762076,0.0005977898,0.001291419,0.001146677,0.001197287,0.0001720289,0.001693294],"genre_scores_gemma":[0.9906753,0.004271537,0.0006567744,0.0005684064,0.0007787627,0.0005220015,0.0008980429,0.00003770581,0.001591433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008410345,"threshold_uncertainty_score":0.02813536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03109704053723129,"score_gpt":0.3220463962443015,"score_spread":0.2909493557070702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}