{"id":"W4379515280","doi":"10.1101/2023.06.05.542485","title":"DNA methylation signatures of early life adversity are exposure-dependent in wild baboons","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"","keywords":"DNA methylation; Genetics; DNA; Methylation; Biology; Psychology; Computational biology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002204661,0.0001520564,0.0002657943,0.000620161,0.0002017661,0.0003161963,0.0001364225,0.000207705,0.001542812],"category_scores_gemma":[0.000484446,0.0002310242,0.0001248376,0.0003744055,0.0002999997,0.0001239921,0.000290659,0.0002364014,0.0002070862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008105957,"about_ca_system_score_gemma":0.00008913029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002745827,"about_ca_topic_score_gemma":0.003499873,"domain_scores_codex":[0.9998358,0.00004415987,0.000009073535,0.00006006613,0.00002086717,0.00003003746],"domain_scores_gemma":[0.999713,0.0000520982,0.000096783,0.00003123763,0.00004331996,0.00006358477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005911559,0.00005361761,0.8482783,0.00003431101,0.0001476001,0.0001450683,0.0004521169,0.0001792135,0.1449754,0.00007588905,0.00007701095,0.004990336],"study_design_scores_gemma":[0.00000187092,0.00006905611,0.9979128,0.000002156198,0.00001415252,0.0001550404,0.0001238371,0.0001506822,0.001417763,0.0000377632,0.0001114423,0.000003382169],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999206,0.0001272538,0.0003025183,0.000006939111,0.000001351081,0.00000208793,0.0002049914,0.000004060221,0.0001448964],"genre_scores_gemma":[0.9992011,0.00007973317,0.0001928337,0.00001369705,0.000002186094,0.000007522376,0.0002776064,0.000004289064,0.0002210661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002745827,"threshold_uncertainty_score":0.005459666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01754218145637732,"score_gpt":0.2320360243914173,"score_spread":0.21449384293504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}