{"id":"W4379518115","doi":"10.1136/annrheumdis-2023-eular.646","title":"POS0116 EFFICACY AND SAFETY OF VOCLOSPORIN ACROSS PATIENT SUBGROUPS WITH PROTEINURIA ≥2 MG/MG: AN INTEGRATED ANALYSIS OF THE AURA-LV AND AURORA 1 STUDIES","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Aurinia (Canada)","funders":"UCB Pharma; Idorsia Pharmaceuticals; Biogen; Amgen; Pfizer; Genentech; Celgene; AstraZeneca; Eli Lilly and Company","keywords":"Proteinuria; Medicine; Urology; Renal biopsy; Internal medicine; Lupus nephritis; Placebo; Creatinine; Gastroenterology; Renal function; Kidney; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004554831,0.00074634,0.00223044,0.0006366428,0.0002953103,0.001419499,0.0003852324,0.000590816,0.002103535],"category_scores_gemma":[0.003318997,0.0002961637,0.004379922,0.001127877,0.0004920681,0.001319868,0.000745366,0.001095025,0.000346496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004580266,"about_ca_system_score_gemma":0.0005594671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004220435,"about_ca_topic_score_gemma":0.001417854,"domain_scores_codex":[0.9974903,0.001236683,0.0003042726,0.0004703044,0.0002781595,0.0002203564],"domain_scores_gemma":[0.9966211,0.001562592,0.001039328,0.0002704896,0.000184144,0.0003223243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.31084,0.0008849588,0.4951893,0.002092589,0.06659569,0.0002704174,0.0002226483,0.001776089,0.01048531,0.0004148637,0.001711007,0.1095171],"study_design_scores_gemma":[0.01562939,0.02105734,0.9179425,0.0002825742,0.03706045,0.000619003,0.0003383747,0.001647997,0.001355283,0.0006584548,0.003285579,0.0001231385],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858786,0.01068492,0.0002920362,0.0001779396,0.00005147072,0.00007184214,0.001369289,0.0000191727,0.001454653],"genre_scores_gemma":[0.9968849,0.001200154,0.0001519539,0.0001367508,0.00005979868,0.00002644357,0.001325667,0.0000102523,0.0002039993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004554831,"threshold_uncertainty_score":0.02408856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06138632291003115,"score_gpt":0.3704596882597784,"score_spread":0.3090733653497473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}