{"id":"W4379518293","doi":"10.1136/annrheumdis-2023-eular.5397","title":"POS0106 INTRA-ARTICULAR MM-II, A NOVEL SUSPENSION OF LARGE EMPTY MULTILAMELLAR LIPOSOMES, IN PAINFUL KNEE OSTEOARTHRITIS: A 26 WEEK PHASE 2B RANDOMIZED TRIAL","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Arthritis Society; Dutch Arthritis Society; Regeneron Pharmaceuticals; Stryker; Pfizer; AstraZeneca; Eli Lilly and Company","keywords":"Medicine; Osteoarthritis; Suspension (topology); Randomized controlled trial; Surgery; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001305319,0.002146155,0.003068111,0.0004324029,0.0003060055,0.001323799,0.0009017804,0.001989243,0.007336347],"category_scores_gemma":[0.0007630356,0.0007179336,0.001746905,0.0004127289,0.001090539,0.001084748,0.0003634127,0.003108202,0.001368247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006378602,"about_ca_system_score_gemma":0.0008575092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009524535,"about_ca_topic_score_gemma":0.001600098,"domain_scores_codex":[0.9996278,0.000152013,0.00001988076,0.00007786162,0.00003301163,0.00008932704],"domain_scores_gemma":[0.9996382,0.00007985291,0.00007550155,0.00002519438,0.00002441094,0.0001567257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9651653,0.006627482,0.0002693708,0.000733523,0.0006723506,0.00003355737,0.00003006088,0.0003101776,0.007436506,0.0001519165,0.0009262581,0.01764348],"study_design_scores_gemma":[0.9044594,0.0926059,0.0007666572,0.00002859046,0.0003778388,0.00002300024,0.00002154843,0.0002834656,0.0007455281,0.0000955098,0.0005738491,0.00001859418],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796569,0.008991739,0.001553809,0.001068088,0.0009052462,0.00318586,0.001628761,0.0002716687,0.00273803],"genre_scores_gemma":[0.9711458,0.005944488,0.002660503,0.002173256,0.0006737295,0.005234633,0.002133494,0.00006424417,0.009969776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007336347,"threshold_uncertainty_score":0.02454251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02593793054535208,"score_gpt":0.3073281547449632,"score_spread":0.2813902241996111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}