{"id":"W4379518426","doi":"10.1136/annrheumdis-2023-eular.5892","title":"OP0200 ORAL DELIVERY OF DELTA-9-TETRAHYDROCANNABINOL PROVIDES SYMPTOM AND DISEASE MODIFICATION USING TWO MODELS OF KNEE OSTEOARTHRITIS","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University Health Network; University of Toronto; Arthritis Society","funders":"Canadian Institutes of Health Research; School of Medicine, University of Missouri; School of Medicine, New York University; Arthritis Society","keywords":"Medicine; Osteoarthritis; WOMAC; Cannabinoid; Cannabinoid receptor; Joint pain; Internal medicine; Synovitis; Anesthesia; Pharmacology; Arthritis; Pathology; Receptor; Agonist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005386516,0.0009471744,0.001086165,0.000839132,0.0005509909,0.0009342391,0.0009235826,0.001339501,0.003273894],"category_scores_gemma":[0.0002720379,0.0005002112,0.001262272,0.0004966105,0.001122739,0.001054309,0.0003094917,0.003622911,0.0007635818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006878672,"about_ca_system_score_gemma":0.001332304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004003296,"about_ca_topic_score_gemma":0.007242525,"domain_scores_codex":[0.999378,0.0000694448,0.00004578226,0.000104751,0.0001118168,0.0002901719],"domain_scores_gemma":[0.999572,0.00004784837,0.00008379794,0.00004979995,0.00005207933,0.0001945421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01490781,0.004321514,0.0001815744,0.0002330983,0.00005353515,0.0001995515,0.0001244085,0.0001877228,0.9742315,0.0003674042,0.0004325973,0.004759302],"study_design_scores_gemma":[0.00205902,0.02906543,0.004230815,0.00004168788,0.0002192212,0.0002727706,0.0004119524,0.00199124,0.9594831,0.0002165914,0.00194133,0.00006673098],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933894,0.001038889,0.001882543,0.0004256839,0.0003670866,0.000143309,0.000699305,0.0001469856,0.001906859],"genre_scores_gemma":[0.9837039,0.001463998,0.002339965,0.0002183412,0.00006588597,0.0002827006,0.0007249573,0.00004069101,0.01115954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004003296,"threshold_uncertainty_score":0.01095229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07482679021949883,"score_gpt":0.3437371317454664,"score_spread":0.2689103415259676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}