{"id":"W4379538020","doi":"10.29011/2575-8241.001303","title":"Efficacy and Safety of a Highly Bioavailable Curcumin Formulation in Modulating Outcomes of Mild Knee Osteoarthritis: Multi-Centric, Randomized, Double-Blind, Placebo-Controlled Study","year":2023,"lang":"en","type":"article","venue":"Journal of Orthopedic Research and Therapy","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Indian Council of Medical Research; OmniActive Health Technologies","keywords":"Osteoarthritis; Curcumin; Placebo; Double blind; Bioavailability; Medicine; Randomized controlled trial; Physical therapy; Pharmacology; Internal medicine; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002403915,0.001045525,0.003336157,0.0006414393,0.000531704,0.0008156589,0.0008195778,0.001515509,0.002669549],"category_scores_gemma":[0.001225163,0.0006474461,0.001255846,0.0004656549,0.001063797,0.0008431306,0.0004532453,0.001506499,0.0004293908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003819418,"about_ca_system_score_gemma":0.0009817184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003750084,"about_ca_topic_score_gemma":0.001012152,"domain_scores_codex":[0.9990595,0.0004137401,0.0001267821,0.0001631452,0.0001246476,0.0001120506],"domain_scores_gemma":[0.9989987,0.0002009356,0.0003324984,0.000112341,0.0001189999,0.0002365025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9033066,0.03745751,0.0007141957,0.00196722,0.001194694,0.00005514008,0.00009476723,0.0002252859,0.03617277,0.00005503475,0.0003209299,0.01843586],"study_design_scores_gemma":[0.5578036,0.4306489,0.004961273,0.00006977733,0.001065307,0.00006104926,0.00004069062,0.0003070814,0.004209393,0.00006262976,0.0007415739,0.00002879883],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899681,0.004724697,0.0009441764,0.0001609695,0.0001970918,0.003123436,0.0003924056,0.00008872931,0.0004004765],"genre_scores_gemma":[0.9891936,0.002913887,0.002098628,0.0003650243,0.0003403212,0.003353673,0.0003938214,0.00001467856,0.001326434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003336157,"threshold_uncertainty_score":0.01271325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06359226332345372,"score_gpt":0.3779455917058828,"score_spread":0.314353328382429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}