{"id":"W4379598232","doi":"10.1242/dev.201606","title":"DNA methylation dynamic in male rat germ cells during gametogenesis","year":2023,"lang":"en","type":"article","venue":"Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Centre hospitalier universitaire de Québec; Université Laval; Institut National de la Recherche Scientifique","funders":"Division of Materials Research; Fonds de recherche du Québec – Nature et technologies; Alliance de recherche numérique du Canada; Perelman School of Medicine, University of Pennsylvania; University of Pennsylvania","keywords":"Biology; Epigenome; Reprogramming; Epigenetics; DNA methylation; Germline; Germ cell; Gametogenesis; Spermatogenesis; Genetics; Chromatin; Gamete; Epigenomics; Reproductive technology; Cell biology; Embryo; Sperm; DNA; Gene; Embryogenesis; Gene expression; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008680754,0.0001170202,0.0001061315,0.0004233961,0.00009955529,0.0001702944,0.00008937908,0.00007165757,0.0009026836],"category_scores_gemma":[0.0001092573,0.00009136226,0.0001075364,0.000174558,0.00009959032,0.00008727358,0.0001540101,0.0001417973,0.0002951763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009464827,"about_ca_system_score_gemma":0.0001470457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001398855,"about_ca_topic_score_gemma":0.002132502,"domain_scores_codex":[0.999953,0.000003447434,0.000001942962,0.00001934975,0.00001193149,0.00001037296],"domain_scores_gemma":[0.9999375,0.000007122616,0.00001716129,0.000006722842,0.00001563712,0.00001582378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009827079,0.000005161647,0.0109966,0.0000275247,0.0000123117,0.00002743387,0.00008485978,0.00008822582,0.9828421,0.0001063269,0.00003411899,0.005676989],"study_design_scores_gemma":[0.000006701534,0.0003375587,0.3627282,0.00001126969,0.00004088851,0.000308442,0.0001909525,0.0006906521,0.632005,0.0001843782,0.003476841,0.00001907209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992857,0.001356628,0.003327151,0.00001617971,0.000007978158,0.000007800379,0.001120578,0.00008536299,0.001221311],"genre_scores_gemma":[0.9947949,0.0007027136,0.00156399,0.00002034459,0.00000327695,0.0000135803,0.0009911351,0.00002427308,0.001885807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001398855,"threshold_uncertainty_score":0.00301975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033107403971796,"score_gpt":0.2499804763028012,"score_spread":0.2396494022630832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}