{"id":"W4379598232","doi":"10.1242/dev.201606","title":"DNA methylation dynamic in male rat germ cells during gametogenesis","year":2023,"lang":"en","type":"article","venue":"Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; Centre hospitalier universitaire de Québec; Université Laval; Institut National de la Recherche Scientifique","funders":"Division of Materials Research; Fonds de recherche du Québec – Nature et technologies; Alliance de recherche numérique du Canada; Perelman School of Medicine, University of Pennsylvania; University of Pennsylvania","keywords":"Biology; Epigenome; Reprogramming; Epigenetics; DNA methylation; Germline; Germ cell; Gametogenesis; Spermatogenesis; Genetics; Chromatin; Gamete; Epigenomics; Reproductive technology; Cell biology; Embryo; Sperm; DNA; Gene; Embryogenesis; Gene expression; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002798309,0.0001142484,0.00009782076,0.0001407069,0.00006189326,0.00001585852,0.00008726971,0.00009849534,0.00002843637],"category_scores_gemma":[0.00002365128,0.0001224692,0.00003384583,0.0002512986,0.0000125285,0.000002779054,0.00009004757,0.00003915767,0.00009444483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005024093,"about_ca_system_score_gemma":0.00007187264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004727761,"about_ca_topic_score_gemma":0.00008253883,"domain_scores_codex":[0.9990784,0.00004124432,0.0002397989,0.0002850393,0.0001293297,0.0002262147],"domain_scores_gemma":[0.9996893,0.000009553914,0.0000547035,0.0001676707,0.0000328235,0.00004590119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000125867,0.00001572747,0.006044852,0.00001793683,0.00001137764,0.000005705092,0.0001275572,0.0009273167,0.9840802,0.000002233865,0.00002760138,0.008726902],"study_design_scores_gemma":[0.0002325089,0.00001279771,0.167864,0.000007538531,0.000002381173,6.717534e-7,0.00002919938,0.0001512986,0.8250915,0.00002377907,0.006446371,0.0001379565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982793,0.0003413665,0.0006416823,0.00004113208,0.0001986878,0.0001499155,0.000002356971,0.00001899523,0.0003265032],"genre_scores_gemma":[0.9944274,0.0004260142,0.001951667,0.0000176118,0.00003197268,0.00004203457,0.0001843603,0.00002032298,0.002898634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1618192,"threshold_uncertainty_score":0.499415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033107403971796,"score_gpt":0.2499804763028012,"score_spread":0.2396494022630832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}