{"id":"W4379600389","doi":"10.1093/brain/awad194","title":"Characteristics of amnestic patients with hypometabolism patterns suggestive of Lewy body pathology","year":2023,"lang":"en","type":"article","venue":"Brain","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; Wallenberg Centre for Molecular and Translational Medicine; European Regional Development Fund; Instituto de Salud Carlos III; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Genentech; Takeda Pharmaceutical Company; IXICO; Novartis Pharmaceuticals Corporation; Junta de Andalucía; National Institutes of Health; Consejería de Salud y Familias, Junta de Andalucía; Knut och Alice Wallenbergs Stiftelse; Servier; Eli Lilly and Company; Lundbeckfonden; Northern California Institute for Research and Education; Universidad de Sevilla; Vetenskapsrådet; BioClinica; Pfizer; Bristol-Myers Squibb Canada; Alzheimer's Association; Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía; GE Healthcare; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; AbbVie; Fujirebio Europe; Alzheimer's Drug Discovery Foundation; Merck; F. Hoffmann-La Roche","keywords":"Lewy body; Pathology; Neuroimaging; Dementia with Lewy bodies; Psychology; Alzheimer's disease; Dementia; Medicine; Lewy body disease; Positron emission tomography; Pathological; Disease; Neuroscience","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002323434,0.0001037641,0.0003262408,0.000245446,0.00002028333,0.000003728728,0.00007065124,0.00004648292,0.0001713037],"category_scores_gemma":[0.0004670031,0.00007931116,0.00004637369,0.0003664328,0.000135901,0.00003532727,0.00006422232,0.0001052938,0.00004001569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001046935,"about_ca_system_score_gemma":0.00007341329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001768833,"about_ca_topic_score_gemma":0.000001748457,"domain_scores_codex":[0.99887,0.00007753188,0.0002430303,0.0001758061,0.0003791533,0.0002544552],"domain_scores_gemma":[0.999096,0.0001885028,0.0001185514,0.0001746615,0.0003361561,0.00008607702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002553765,0.0003634058,0.9852276,0.0001825356,0.00006178768,0.0001092676,0.0002079238,9.452312e-8,0.004121964,0.00008925111,0.0002798282,0.009100975],"study_design_scores_gemma":[0.002111551,0.001178788,0.9936082,0.0001243348,0.00007763691,0.0000065406,0.00009598872,0.00001669519,0.002420363,0.00004112938,0.0002480996,0.00007069636],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983877,0.00001069419,0.0001820926,0.0003170636,0.00005934635,0.0004029906,0.0001977251,0.00002685251,0.0004155559],"genre_scores_gemma":[0.9985596,0.0000248118,0.00005143818,0.0001422587,0.00003655678,0.00002594526,0.0003015244,0.00001839458,0.0008394685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009030279,"threshold_uncertainty_score":0.3234215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009659090366511946,"score_gpt":0.2777966461496384,"score_spread":0.2681375557831264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}