{"id":"W4379600389","doi":"10.1093/brain/awad194","title":"Characteristics of amnestic patients with hypometabolism patterns suggestive of Lewy body pathology","year":2023,"lang":"en","type":"article","venue":"Brain","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; Wallenberg Centre for Molecular and Translational Medicine; European Regional Development Fund; Instituto de Salud Carlos III; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Genentech; Takeda Pharmaceutical Company; IXICO; Novartis Pharmaceuticals Corporation; Junta de Andalucía; National Institutes of Health; Consejería de Salud y Familias, Junta de Andalucía; Knut och Alice Wallenbergs Stiftelse; Servier; Eli Lilly and Company; Lundbeckfonden; Northern California Institute for Research and Education; Universidad de Sevilla; Vetenskapsrådet; BioClinica; Pfizer; Bristol-Myers Squibb Canada; Alzheimer's Association; Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía; GE Healthcare; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; AbbVie; Fujirebio Europe; Alzheimer's Drug Discovery Foundation; Merck; F. Hoffmann-La Roche","keywords":"Lewy body; Pathology; Neuroimaging; Dementia with Lewy bodies; Psychology; Alzheimer's disease; Dementia; Medicine; Lewy body disease; Positron emission tomography; Pathological; Disease; Neuroscience","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003519979,0.0003751315,0.0003869027,0.001051842,0.0003995091,0.0006418114,0.0002564865,0.0003916352,0.001097595],"category_scores_gemma":[0.002743421,0.0002238682,0.0002467918,0.0006787825,0.0003413014,0.0003754361,0.000369659,0.0003124519,0.0003948422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002042951,"about_ca_system_score_gemma":0.0002189169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001755116,"about_ca_topic_score_gemma":0.001792814,"domain_scores_codex":[0.9997717,0.00003481679,0.00006196035,0.00005643744,0.0000426891,0.00003248699],"domain_scores_gemma":[0.9985639,0.0003186378,0.0006687211,0.00009131625,0.0001279111,0.000229343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002602866,0.00003570355,0.9958675,0.000006140415,0.00002201976,0.001097783,0.0001440365,0.00004233332,0.000954164,0.00001370521,0.00005543756,0.001500976],"study_design_scores_gemma":[0.00001688018,0.0001576532,0.9926372,0.000006637631,0.00002202449,0.006360066,0.0003179969,0.000157005,0.0001270214,0.00004716039,0.0001433177,0.000007122409],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994841,0.0001083557,0.00002970473,0.00001362208,0.000002215923,0.000004905618,0.00007422874,0.000003144504,0.0002797492],"genre_scores_gemma":[0.9995431,0.00006410644,0.00004580118,0.00001738388,0.000008059892,0.000006024647,0.0002317659,0.000001401684,0.00008248074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001755116,"threshold_uncertainty_score":0.003671825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009659090366511946,"score_gpt":0.2777966461496384,"score_spread":0.2681375557831264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}