{"id":"W4379600933","doi":"10.1042/bcj20230167","title":"Mitochondrial metabolism and dynamics in pancreatic beta cell glucose sensing","year":2023,"lang":"en","type":"review","venue":"Biochemical Journal","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; National Institutes of Health; Diabetes UK; Wellcome Trust; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Carbohydrate metabolism; Beta cell; Glucose transporter; GLUT4; Biology; Secretion; Mitochondrion; Incretin; Glucose uptake; Insulin; Islet; Cell metabolism; Cell biology; Metabolism; Endocrinology; Diabetes mellitus; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004544021,0.0007022339,0.001006129,0.001478683,0.0002904122,0.001083505,0.0006441363,0.0009193982,0.002062581],"category_scores_gemma":[0.0004254123,0.0002402254,0.0003019465,0.001942668,0.0005021158,0.001552062,0.0008028915,0.001475646,0.001861575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007420467,"about_ca_system_score_gemma":0.000856575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000974924,"about_ca_topic_score_gemma":0.001556853,"domain_scores_codex":[0.9998945,0.00001721576,0.00001884858,0.00001790815,0.0000368578,0.00001467492],"domain_scores_gemma":[0.9998363,0.00005178832,0.00002756649,0.000005320935,0.00005708805,0.00002187698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001405659,0.00005588014,0.0002200433,0.01255942,0.00005529827,0.0003203486,0.00009221535,0.0004673316,0.003876116,0.005888789,0.02979056,0.9465334],"study_design_scores_gemma":[0.00001495011,0.0001040869,0.00111248,0.002231539,0.0000601315,0.001507567,0.00008369741,0.0001098687,0.0006366559,0.003216173,0.990903,0.00001983159],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009503291,0.9988167,0.00005753202,0.0002656605,0.0002171828,0.000001326376,0.000005234562,0.000004006346,0.000537325],"genre_scores_gemma":[0.0005673574,0.9986987,0.00006833394,0.0001300189,0.0001549499,0.000002031133,0.00001038416,7.233219e-7,0.0003674755],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002062581,"threshold_uncertainty_score":0.006900072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03198162582310671,"score_gpt":0.3014919854636866,"score_spread":0.2695103596405798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}