{"id":"W4379600933","doi":"10.1042/bcj20230167","title":"Mitochondrial metabolism and dynamics in pancreatic beta cell glucose sensing","year":2023,"lang":"en","type":"review","venue":"Biochemical Journal","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; National Institutes of Health; Diabetes UK; Wellcome Trust; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Carbohydrate metabolism; Beta cell; Glucose transporter; GLUT4; Biology; Secretion; Mitochondrion; Incretin; Glucose uptake; Insulin; Islet; Cell metabolism; Cell biology; Metabolism; Endocrinology; Diabetes mellitus; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002657083,0.0003968902,0.002080241,0.0004012985,0.00005644595,0.00007771543,0.00009655178,0.0004807625,0.00003980959],"category_scores_gemma":[0.0004682613,0.0002938517,0.0004385059,0.0004234551,0.0001275856,0.00003888485,0.00008178465,0.001107476,0.00007489379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003303103,"about_ca_system_score_gemma":0.0003688803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001652113,"about_ca_topic_score_gemma":0.000001463333,"domain_scores_codex":[0.9979174,0.0001341447,0.0008583086,0.0003520144,0.0003325791,0.0004056171],"domain_scores_gemma":[0.9985776,0.0003830463,0.0003109682,0.0002374084,0.00006527945,0.0004257244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002806052,0.0004319924,0.000166727,0.04387389,0.001360134,0.001719142,0.0001102446,1.997276e-7,0.00449959,0.0001963534,0.01514198,0.9322191],"study_design_scores_gemma":[0.006964585,0.0002151922,0.00007200878,0.06572456,0.01269698,0.006343839,0.0003344487,0.0006639918,0.001426546,0.0003882689,0.9037405,0.001429111],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005937421,0.9921566,0.00002830516,0.00009589509,0.0007428368,0.0003710897,0.00002530509,0.00004486532,0.0005976471],"genre_scores_gemma":[0.00004402124,0.9957145,0.001862009,0.00007849105,0.001507638,0.000005881005,0.0001174421,0.00007355667,0.000596449],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.93079,"threshold_uncertainty_score":0.9999514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03198162582310671,"score_gpt":0.3014919854636866,"score_spread":0.2695103596405798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}