{"id":"W4379645970","doi":"10.1200/jco.2023.41.17_suppl.lba4","title":"SWOG S1826, a randomized study of nivolumab(N)-AVD versus brentuximab vedotin(BV)-AVD in advanced stage (AS) classic Hodgkin lymphoma (HL).","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; SickKids Foundation; Princess Margaret Cancer Centre; Hospital for Sick Children; McGill University Health Centre","funders":"","keywords":"Medicine; Internal medicine; Neutropenia; Brentuximab vedotin; Clinical endpoint; Oncology; Nivolumab; Randomized controlled trial; Chemotherapy; Cancer; Lymphoma; Hodgkin lymphoma; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002206416,0.001577449,0.002033936,0.0003844705,0.0003669269,0.001075627,0.0009779475,0.001353682,0.00708689],"category_scores_gemma":[0.001969068,0.0006402959,0.001760389,0.0003359205,0.001009659,0.001018377,0.0004253442,0.002941857,0.0009281669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009251328,"about_ca_system_score_gemma":0.001409156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008807543,"about_ca_topic_score_gemma":0.002435989,"domain_scores_codex":[0.9992975,0.0004672118,0.00003686236,0.00008188479,0.00003684057,0.0000797518],"domain_scores_gemma":[0.9988173,0.0003281804,0.0003189315,0.00006132865,0.00006235922,0.0004118402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9815151,0.003926554,0.0007897879,0.0004210583,0.000659525,0.00003111462,0.00003460629,0.0003443075,0.00115341,0.0001191235,0.0009370107,0.01006834],"study_design_scores_gemma":[0.9195986,0.0760085,0.001585618,0.00005866925,0.0005447905,0.00004960871,0.00002712447,0.0005282867,0.0002827586,0.0002511884,0.001052235,0.00001259329],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850242,0.004366826,0.0006433033,0.0008574266,0.0007256545,0.004224194,0.001608784,0.0001135525,0.002436066],"genre_scores_gemma":[0.9858249,0.002239661,0.001376436,0.001216512,0.0003846699,0.004386257,0.00128992,0.00002933102,0.003252232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00708689,"threshold_uncertainty_score":0.02370805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.126440877175517,"score_gpt":0.4876273556058542,"score_spread":0.3611864784303372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}