{"id":"W4379649688","doi":"10.1136/annrheumdis-2023-eular.1917","title":"POS1538 SAFETY OF GUSELKUMAB ACROSS DIVERSE PATIENT SUBGROUPS WITH PSORIATIC DISEASE: AN INTEGRATED ANALYSIS OF 11 PHASE 2/3 CLINICAL STUDIES IN PSORIASIS AND PSORIATIC ARTHRITIS","year":2023,"lang":"en","type":"article","venue":"","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"UCB Pharma; Sun Pharma; National Institute for Health and Care Research; Gilead Sciences; Amgen; Pfizer; Celgene; AstraZeneca; Eli Lilly and Company","keywords":"Psoriatic arthritis; Medicine; Psoriasis; Dermatology; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01227685,0.0008773153,0.00238787,0.001124147,0.0003626234,0.001694357,0.0005329832,0.0006729468,0.003255366],"category_scores_gemma":[0.007548423,0.0003618647,0.006908943,0.001753081,0.000551066,0.0008374107,0.0008231932,0.0009332395,0.0004669923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008381164,"about_ca_system_score_gemma":0.001778507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000387727,"about_ca_topic_score_gemma":0.001441698,"domain_scores_codex":[0.9919016,0.004192329,0.001105737,0.001091977,0.001350156,0.0003583361],"domain_scores_gemma":[0.9934986,0.002289407,0.002609657,0.0005775992,0.0006157854,0.0004089824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.3366222,0.002527371,0.3011873,0.00863558,0.1269729,0.0004642275,0.0003994261,0.003815643,0.02380537,0.0004253986,0.006263274,0.1888812],"study_design_scores_gemma":[0.03667336,0.06869936,0.7214485,0.0007094411,0.1406354,0.001427804,0.0003710096,0.004231411,0.008210432,0.001031373,0.01635528,0.0002066577],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9384394,0.03507839,0.005479287,0.0008388814,0.0001322988,0.003717882,0.01310634,0.0002003096,0.003007101],"genre_scores_gemma":[0.9796398,0.003997521,0.003658517,0.0008617599,0.0001993248,0.001560346,0.009469365,0.00006187448,0.0005514155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01227685,"threshold_uncertainty_score":0.06492698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05197030421202719,"score_gpt":0.3548272804716721,"score_spread":0.3028569762596449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}