{"id":"W4379650122","doi":"10.1136/annrheumdis-2023-eular.2062","title":"AB0396 DISCONTINUATION AND EFFECTIVENESS OF ORIGINATOR AND BIOSIMILAR TNFI IN PATIENTS WITH RHEUMATOID ARTHRITIS: REAL WORLD DATA FROM A RHEUMATOID ARTHRITIS REGISTRY IN CANADA","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University of Toronto; Ministry of Health and Long Term Care","funders":"Canadian Institutes of Health Research","keywords":"Biosimilar; Medicine; Discontinuation; Rheumatoid arthritis; Internal medicine; Real world data; Arthritis; Physical therapy; Data science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001821714,0.0002927355,0.00096185,0.001786508,0.001306071,0.002457552,0.001736459,0.0009481356,0.001832199],"category_scores_gemma":[0.00844213,0.0005046064,0.001186318,0.008274321,0.001086097,0.0006765711,0.0007411371,0.001339093,0.000249353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.02345017,"about_ca_system_score_gemma":0.02608293,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9651643,"about_ca_topic_score_gemma":0.9609993,"domain_scores_codex":[0.9957496,0.0004556146,0.0004839457,0.000651882,0.001611443,0.001047532],"domain_scores_gemma":[0.9833966,0.001593772,0.007530742,0.0006865273,0.004613035,0.002179361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002886114,0.00002282756,0.9968799,0.00003508021,0.0001146104,0.00008368822,0.0001662307,0.00008462709,0.00005995227,0.00004891753,0.0006593835,0.001555975],"study_design_scores_gemma":[0.00003700885,0.00003794256,0.998555,0.00002513122,0.00008121151,0.0001286937,0.0003833139,0.0001843383,0.0000354449,0.00001393665,0.0005050427,0.00001286039],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848429,0.00214095,0.00008469907,0.0005328165,0.00001777139,0.00003539471,0.01037132,0.00001764364,0.001956675],"genre_scores_gemma":[0.9952092,0.0008695911,0.00009435992,0.0001930704,0.0000159202,0.00001119435,0.003166773,0.00001084213,0.0004291022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0348357,"threshold_uncertainty_score":0.1701437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02507797314022757,"score_gpt":0.2789506569275707,"score_spread":0.2538726837873431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}