{"id":"W4379650518","doi":"10.1136/annrheumdis-2023-eular.3918","title":"AB0947 EFFECT OF UPADACITINIB ON REDUCING PAIN IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS AND INADEQUATE RESPONSE TO BIOLOGIC THERAPY","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Ankylosing spondylitis; Placebo; Clinical endpoint; Internal medicine; BASDAI; Minimal clinically important difference; Secukinumab; Low back pain; Back pain; Randomized controlled trial; Physical therapy; Psoriatic arthritis; Arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004173522,0.0004638709,0.001794904,0.0002731489,0.0002574383,0.0005244586,0.0003279474,0.0006271115,0.005754869],"category_scores_gemma":[0.0009302965,0.0002055514,0.001092587,0.0002589362,0.0002358849,0.00043845,0.0002587257,0.001699602,0.0005964609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002817725,"about_ca_system_score_gemma":0.0005291099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001619264,"about_ca_topic_score_gemma":0.004016334,"domain_scores_codex":[0.9997783,0.00006563468,0.00002662468,0.00002259795,0.00003000367,0.0000767817],"domain_scores_gemma":[0.9996551,0.0001112675,0.00005295666,0.00001664329,0.00003522084,0.0001287817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5347756,0.01510909,0.01669275,0.0027923,0.003556926,0.001049861,0.0001562052,0.001855159,0.0242333,0.0005181944,0.008607892,0.3906527],"study_design_scores_gemma":[0.2968183,0.3380557,0.3137526,0.001317491,0.00713267,0.004595737,0.0007923235,0.008211004,0.007880136,0.0008782895,0.0203446,0.0002212181],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770082,0.01463442,0.0001190975,0.001184067,0.0004982662,0.0001508551,0.0005641795,0.00007433692,0.005766528],"genre_scores_gemma":[0.9937711,0.003613237,0.0002821745,0.0006056096,0.0001708352,0.00006496508,0.000529971,0.000005707081,0.0009563995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005754869,"threshold_uncertainty_score":0.01925194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02449865578999377,"score_gpt":0.31051058484283,"score_spread":0.2860119290528362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}